Aprindine - Misplaced Pages

Antiarrhythmic drug Pharmaceutical compound

Aprindine
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	C01BB04 (WHO)
Identifiers
IUPAC name {3-propyl}diethylamine
CAS Number	37640-71-4
PubChem CID	2218
DrugBank	DB01429
ChemSpider	2132
UNII	5Y48085P9Q
KEGG	D02969
ChEMBL	ChEMBL1213033
CompTox Dashboard (EPA)	DTXSID3022615
Chemical and physical data
Formula	C₂₂H₃₀N₂
Molar mass	322.496 g·mol
3D model (JSmol)	Interactive image
SMILES c1cccc3c1CC(N(c2ccccc2)CCCN(CC)CC)C3
InChI InChI=1S/C22H30N2/c1-3-23(4-2)15-10-16-24(21-13-6-5-7-14-21)22-17-19-11-8-9-12-20(19)18-22/h5-9,11-14,22H,3-4,10,15-18H2,1-2H3 Key:NZLBHDRPUJLHCE-UHFFFAOYSA-N
(verify)

Aprindine is a Class 1b antiarrhythmic agent.

References

"WHOCC - ATC/DDD Index". WHO Collaborating Centre for Drug Statistics Methodology. Retrieved 2018-03-01.

class Ia (Phase 0→ and Phase 3→)	Ajmaline Disopyramide Hydroquinidine Lorajmine Prajmaline Procainamide Quinidine Sparteine
class Ib (Phase 3←)	IV Lidocaine enteral Aprindine Mexiletine Tocainide
class Ic (Phase 0→)	Encainide Ethacizine Flecainide Indecainide Lorcainide Moracizine Propafenone

class II (Phase 4→, β blockers)	Nadolol Pindolol Propranolol cardioselective Acebutolol Atenolol Esmolol Landiolol Metoprolol
A₁ agonist	Adenosine Benzodiazepines Barbiturates
M₂	muscarinic antagonist: Atropine Disopyramide Quinidine muscarinic agonist: Digoxin
α receptors	Amiodarone Bretylium Quinidine Verapamil

Na/ K-ATPase	Digitoxin Digoxin Ouabain

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