Aqualysin 1 | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 3.4.21.111 | ||||||||
CAS no. | 88747-68-6 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
|
Aqualysin 1 (EC 3.4.21.111, caldolysin) is an enzyme. This enzyme catalyses the following chemical reaction
- Exhibits low specificity towards esters of amino acids with small hydrophobic or aromatic residues at the P1 position
This enzyme is isolated from the thermophile, Thermus aquaticus.
References
- Matsuzawa H, Tokugawa K, Hamaoki M, Mizoguchi M, Taguchi H, Terada I, Kwon ST, Ohta T (February 1988). "Purification and characterization of aqualysin I (a thermophilic alkaline serine protease) produced by Thermus aquaticus YT-1". European Journal of Biochemistry. 171 (3): 441–7. doi:10.1111/j.1432-1033.1988.tb13809.x. PMID 3162211.
- Tanaka T, Matsuzawa H, Kojima S, Kumagai I, Miura K, Ohta T (October 1998). "P1 specificity of aqualysin I (a subtilisin-type serine protease) from Thermus aquaticus YT-1, using P1-substituted derivatives of Streptomyces subtilisin inhibitor". Bioscience, Biotechnology, and Biochemistry. 62 (10): 2035–8. doi:10.1271/bbb.62.2035. PMID 9882104.
- Tanaka T, Matsuzawa H, Ohta T (1998). "Substrate Specificity of Aqualysin I, a Bacterial Thermophilic Alkaline Serine Protease from Thermus aquaticus YT-1: Comparison with Proteinase K, Subtilisin BPN' and Subtilisin Carlsberg". Bioscience, Biotechnology, and Biochemistry. 62 (11): 2161–5. doi:10.1271/bbb.62.2161.
External links
- Aqualysin+1 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Endopeptidases: serine proteases/serine endopeptidases (EC 3.4.21) | |
---|---|
Digestive enzymes | |
Coagulation | |
Complement system | |
Other immune system | |
Venombin | |
Other |
Enzymes | |
---|---|
Activity | |
Regulation | |
Classification | |
Kinetics | |
Types |
|