Archain 1 is a protein that in humans is encoded by the ARCN1 gene.
Function
This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or vesicle trafficking.
References
- ^ GRCh38: Ensembl release 89: ENSG00000095139 – Ensembl, May 2017
- ^ GRCm38: Ensembl release 89: ENSMUSG00000032096 – Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Archain 1". Retrieved 2016-06-22.
Further reading
- Deng K, Gao F, Zheng P, Gong W, Sun Z (2012). "Crystallization and preliminary X-ray analysis of the C-terminal domain of δ-COP, a medium-sized subunit of the COPI complex involved in membrane trafficking". Acta Crystallographica Section F. 68 (Pt 7): 829–31. doi:10.1107/S1744309112022798. PMC 3388933. PMID 22750876.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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