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Chemical and physical data | |
Formula | C16H17N |
Molar mass | 223.319 g·mol |
3D model (JSmol) | |
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BW-247 is an antidepressant.
BW-247 is a secondary amine, closely related in structure to the tricyclic antidepressants, which inhibits NA uptake in aortic strips and rat cerebral cortex slices. Unlike the tricyclic antidepressants, it is reported not to possess anticholinergic activity.
See also
References
- Castañer, J., Roberts, P. J. (1979). "BW-247". Drugs of the Future. 4 (2): 92. doi:10.1358/dof.1979.004.02.1002432.
- Ankier, S. I. (1986). "Progress in Medicinal Chemistry". 4 Recent Progress in the Development of New Antidepressant Drugs. Vol. 23. Elsevier. pp. 121–185. doi:10.1016/S0079-6468(08)70342-4.
- R.A. Maxwell, P.D. Keenan, E. Chaplin, B. Roth and S. Batimanglidj Eckhardt, J. Pharmacol. Exp. Ther., 166 (1969) 320.
- A.I. Salama, J.R. Insalaco and R.A. Maxwell, J. Pharmacol. Exp. Ther., 178 (1971) 474.
- J.W. Bridges, J.G. Dent and P. Johnson, Life Sci., 18 (1976) 97.
Monoamine reuptake inhibitors | |||||||||||||||
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DATTooltip Dopamine transporter (DRIsTooltip Dopamine reuptake inhibitors) |
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NETTooltip Norepinephrine transporter (NRIsTooltip Norepinephrine reuptake inhibitors) |
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SERTTooltip Serotonin transporter (SRIsTooltip Serotonin reuptake inhibitors) |
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VMATsTooltip Vesicular monoamine transporters | |||||||||||||||
Others |
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See also: Receptor/signaling modulators • Monoamine releasing agents • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins |