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| IUPAC name (2S)-N--2-aminopropanamide | |
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| Chemical formula | C14H20Cl2N2O6 |
| Molar mass | 383.22 g·mol |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references | |
Bactobolin is a cytotoxic, polyketide-peptide and antitumor antibiotic with the molecular formula C14H20Cl2N2O6. Bactobolin was discovered in 1979.
References
- ^ "Bactobolin". Pubchem.ncbi.NLM.nih.gov.
- Greenberg, E. Peter; Chandler, Josephine R.; Seyedsayamdost, Mohammad R. (27 March 2020). "The Chemistry and Biology of Bactobolin: A 10-Year Collaboration with Natural Product Chemist Extraordinaire Jon Clardy". Journal of Natural Products. 83 (3): 738–743. doi:10.1021/acs.jnatprod.9b01237. hdl:1808/32425. PMC 8118907. PMID 32105069.
- Weinreb, Steven M. (1995). "Total synthesis of the microbial antitumor antibiotics actinobolin and bactobolin". Studies in Natural Products Chemistry. 16: 3–25. doi:10.1016/S1572-5995(06)80051-7. ISBN 9780444822642.
- Munakata, Tomohiko; Ikeda, Yoshifumi; Matsuki, Hideo; Isagai, Katsuyoshi (May 1983). "Cultural Conditions and Strain Improvement for Production of Bactobolin". Agricultural and Biological Chemistry. 47 (5): 929–934. doi:10.1080/00021369.1983.10865772.
- Franco, Carlos M.; Belda, Beatriz Vázquez (2 December 2020). Natural Compounds as Antimicrobial Agents. MDPI. p. 134. ISBN 978-3-03936-048-2.
- Reinhoudt, D. N.; Connors, T. A.; Pinedo, H. M.; Poll, K. W. van de (6 December 2012). Structure-Activity Relationships of Anti-Tumour Agents. Springer Science & Business Media. p. 270. ISBN 978-94-009-6798-4.
Further reading
- Weinreb, S. M.; Garigipati, R. S. (1 January 1989). "Design of an efficient strategy for total synthesis of the microbial metabolite (-)-bactobolin". Pure and Applied Chemistry. 61 (3): 435–438. doi:10.1351/pac198961030435.
- Lukacs, Gabor; Ohno, Masaji (6 December 2012). Recent Progress in the Chemical Synthesis of Antibiotics. Springer Science & Business Media. p. 286. ISBN 978-3-642-75617-7.
- Kocienski, Philip J. (14 May 2014). Protecting Groups, 3rd Edition 2005. Georg Thieme Verlag. p. 554. ISBN 978-3-13-179153-5.
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