Binding domain - Misplaced Pages

(Redirected from Binding domains) Region of a protein which can bind to biomolecules with chemical specificity

In molecular biology, binding domain is a protein domain which binds to a specific atom or molecule, such as calcium or DNA. A protein domain is a part of a protein sequence and a tertiary structure that can change or evolve, function, and live by itself independent of the rest of the protein chain. Upon binding, proteins may undergo a conformational change. Binding domains are essential for the function of many proteins. They are essential because they help splice, assemble, and translate proteins.

Examples of binding domains include the Zinc finger, which binds to DNA, and EF hand, which binds to calcium.

References

Phillips, DC. (1966). "The three-dimensional structure of an enzyme molecule". Scientific American. 215 (5): 78–90. doi:10.1038/scientificamerican1166-78. PMID 5978599.
Yong, J., T. J. Golembe, D. J. Battle, L. Pellizzoni, and G. Dreyfuss. "SnRNAs Contain Specific SMN-binding Domains That Are Essential for SnRNP Assembly". Molecular and Cellular Biology. U.S. National Library of Medicine, April 2004. Retrieved April 2017.

v t e Proteins
Processes	Protein biosynthesis Post-translational modification Protein folding Protein targeting Proteome Protein methods
Structures	Protein structure Protein structural domains Proteasome
Types	List of proteins Membrane protein Globular protein Globulin Edestin Albumin Fibrous protein Chromoprotein Photoreceptor protein Biliprotein Phycobiliprotein Phytochrome Lipocalin

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