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Butaxamine

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(Redirected from Butoxamine) Mixture of isomers Pharmaceutical compound
Butaxamine
Clinical data
Other namesButoxamine
ATC code
  • None
Identifiers
IUPAC name
  • (1S,2S)-1-(2,5-Dimethoxyphenyl)-2-(tert-butylamino)propan-1-ol
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC15H25NO3
Molar mass267.369 g·mol
3D model (JSmol)
SMILES
  • C((C1=C(C=CC(=C1)OC)OC)O)NC(C)(C)C
InChI
  • InChI=1S/C15H25NO3/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6/h7-10,14,16-17H,1-6H3/t10-,14-/m0/s1
  • Key:TWUSDDMONZULSC-HZMBPMFUSA-N
  (verify)

Butaxamine (INN; also known as butoxamine) is a β2-selective beta blocker. Its primary use is in experimental situations in which blockade of β2 receptors is necessary to determine the activity of the drug (i.e. if the β2 receptor is completely blocked, but the given effect is still present, the given effect is not a characteristic of the β2 receptor). It has no clinical use. An alternative name is α-(1-ethyl)-2,5-dimethoxybenzyl alcohol.

See also

References

  1. "Definition: butoxamine from Online Medical Dictionary".
  2. Hillman KL, Doze VA, Porter JE (August 2005). "Functional characterization of the beta-adrenergic receptor subtypes expressed by CA1 pyramidal cells in the rat hippocampus". J. Pharmacol. Exp. Ther. 314 (2): 561–7. doi:10.1124/jpet.105.084947. PMID 15908513. S2CID 12446381.
Beta blockers (C07)
β, non-selective
β1-selective
β2-selective
α1- + β-selective
Adrenergic receptor modulators
α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists


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