Misplaced Pages

CCDC151

Article snapshot taken from[REDACTED] with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Protein-coding gene in humans
ODAD3
Identifiers
AliasesODAD3, CILD30, coiled-coil domain containing 151, ODA10, CCDC151, outer dynein arm docking complex subunit 3
External IDsOMIM: 615956; MGI: 1924859; HomoloGene: 16533; GeneCards: ODAD3; OMA:ODAD3 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)
Chromosome 19 (human)Genomic location for ODAD3Genomic location for ODAD3
Band19p13.2Start11,420,604 bp
End11,435,782 bp
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)
Chromosome 9 (mouse)Genomic location for ODAD3Genomic location for ODAD3
Band9|9 A3Start21,901,167 bp
End21,913,930 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • bronchial epithelial cell

  • right uterine tube

  • gonad

  • nasal epithelium

  • mucosa of paranasal sinus

  • olfactory zone of nasal mucosa

  • testicle

  • left testis

  • right testis

  • Pituitary Gland
Top expressed in
  • seminiferous tubule

  • otolith organ

  • utricle

  • spermatocyte

  • morula

  • spermatid

  • olfactory epithelium

  • Epithelium of choroid plexus

  • embryo

  • embryo
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

115948

77609

Ensembl

ENSG00000198003

ENSMUSG00000039632

UniProt

A5D8V7

Q8BSN3

RefSeq (mRNA)

NM_145045
NM_001302453
NM_001302454

NM_001163787
NM_029939

RefSeq (protein)

NP_001289382
NP_001289383
NP_659482

NP_001157259
NP_084215

Location (UCSC)Chr 19: 11.42 – 11.44 MbChr 9: 21.9 – 21.91 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Coiled-coil domain containing 151 is a protein that in humans is encoded by the CCDC151 gene.

Clinical significance

Mutations in CCDC151 are associated to Primary ciliary dyskinesia.

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000198003 – Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000039632 – Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Coiled-coil domain containing 151".
  6. Alsaadi MM, Erzurumluoglu AM, Rodriguez S, Guthrie PA, Gaunt TR, Omar HZ, Mubarak M, Alharbi KK, Al-Rikabi AC, Day IN (December 2014). "Nonsense mutation in coiled-coil domain containing 151 gene (CCDC151) causes primary ciliary dyskinesia". Human Mutation. 35 (12): 1446–8. doi:10.1002/humu.22698. PMC 4489323. PMID 25224326.

Further reading

  • Jerber J, Baas D, Soulavie F, Chhin B, Cortier E, Vesque C, Thomas J, Durand B (February 2014). "The coiled-coil domain containing protein CCDC151 is required for the function of IFT-dependent motile cilia in animals". Human Molecular Genetics. 23 (3): 563–77. doi:10.1093/hmg/ddt445. PMID 24067530.

External links

Stub icon

This article on a gene on human chromosome 19 is a stub. You can help Misplaced Pages by expanding it.

Categories:
CCDC151 Add topic