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Cardinal Sin, cardinal sin, or cardinal syn may refer to:

Sins

• Seven deadly sins, often called the "cardinal sins"
• Mortal sin (Catholicism)
• The three cardinal sins in Judaism, see Self-sacrifice in Jewish law

People

• Jaime Sin (1928–2005), Filipino cardinal and archbishop of Jaro (1972–1974) and Manila (1974–2003)

Music

• Cardinal Sin (band), a black metal band formed in 1995
• "Cardinal Sin", a song by Black Sabbath from their 1994 album Cross Purposes
• "The Cardinal Sin", a song by Dead Can Dance from their 1985 album Spleen and Ideal
• "Cardinal Sin", a song by Powerwolf from their 2013 album Preachers of the Night

Other arts and entertainment

• Cardinal Syn, a 1998 3D fighting game for the PlayStation
• The Cardinal Sins, a novel by Andrew Greeley
• Cardinal Sin (Banksy), a sculpture by graffiti artist Banksy

• Disambiguation pages