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The channelosome (not to be confused with "channelome") is the collection of (usually) signalling proteins associated with an ion channel. The channelosome is frequently clustered within a lipid microdomain or caveolae. This collection of proteins may be involved with anchoring, phosphorylation or some other modulatory or support function. An example is neural KCNQ/M (Kv7) potassium channelosome (see Delmas & Brown, 2005).
References
Delmas, P.; Brown, D. A. (2005). "Pathways modulating neural KCNQ/M (Kv7) potassium channels". Nature Reviews Neuroscience. 6 (11): 850–62. doi:10.1038/nrn1785. PMID 16261179. S2CID 8820080.
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