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Chrome Azurol S

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Microbial stain
Chrome Azurol S
Names
Preferred IUPAC name Trisodium 5--3-methyl-2-oxidobenzoate
Other names
  • Mordant Blue 29
  • C.I. 43825
  • Alberon
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.015.262 Edit this at Wikidata
EC Number
  • 216-787-0
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C23H16Cl2O9S.3Na/c1-9-5-11(7-13(20(9)26)22(28)29)17(12-6-10(2)21(27)14(8-12)23(30)31)18-15(24)3-4-16(19(18)25)35(32,33)34;;;/h3-8,26H,1-2H3,(H,28,29)(H,30,31)(H,32,33,34);;;/q;3*+1/p-3/b17-12+;;;Key: FUIZKNBTOOKONL-DPSBJRLESA-K
SMILES
  • CC1=CC(=CC(=C1)C(=O))C(=C2C=C(C(=O)C(=C2)C(=O)O)C)C3=C(C=CC(=C3Cl)S(=O)(=O))Cl...
Properties
Chemical formula C23H13Cl2Na3O9S
Molar mass 605.28 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Chrome Azurol S is a histological dye used in biomedical research.

Chrome Azural S (CAS) is a common spectrophotometric reagent for detection of certain metals like aluminum which can be toxic in excess and can contribute to people with neurodegenerative disorders. CAS is used to provide quantitative and qualitative information on molecules of interest like aluminum and siderophores. Qualitatively a color change can be observed while also allowing to quantitatively determine concentration of certain ions.

References

  1. Berger, Selman A.; McKay, J. Brian (July 1974). "The photometric titration of Fe(III) with EDTA using tiron indicator". Microchimica Acta. 62 (4): 665–670. doi:10.1007/bf01218204. PMID 4216747. S2CID 32908378.
  2. Alexander, D.; Zuberer, David (1991-09-01). "Use of chrome azurol S reagents to evaluate siderophore production by rhizosphere bacteria". Biology and Fertility of Soils. 12 (1): 39–45. Bibcode:1991BioFS..12...39A. doi:10.1007/BF00369386. S2CID 25744344.
  3. Ngarisan, Noor Izyan; Ngah, Che Wan Zanariah Che Wan; Ahmad, Musa; Kuswandi, Bambang (2014-11-01). "Optimization of polymer inclusion membranes (PIMs) preparation for immobilization of Chrome Azurol S for optical sensing of aluminum(III)". Sensors and Actuators B: Chemical. 203: 465–470. Bibcode:2014SeAcB.203..465N. doi:10.1016/j.snb.2014.07.023. ISSN 0925-4005.
  4. Himpsl, Stephanie D.; Mobley, Harry L. T. (2019). "Siderophore Detection Using Chrome Azurol S and Cross-Feeding Assays". Proteus mirabilis. Methods in Molecular Biology. Vol. 2021. pp. 97–108. doi:10.1007/978-1-4939-9601-8_10. ISBN 978-1-4939-9600-1. ISSN 1940-6029. PMID 31309499. S2CID 196813888.


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