Article snapshot taken from[REDACTED] with creative commons attribution-sharealike license.
Give it a read and then ask your questions in the chat.
We can research this topic together.
Delayed pressure urticaria is known as one of the more painful subsets of physical urticaria due to formed hives being deep-seated and appearing after 4–6 hours.
Causes
Due to the delayed appearance of wheals, plausible causes are hard to establish; the natural course and/or clinical pattern is variable and inconclusive.
Treatment
It was noted that although antihistamines and anti-inflammatory drugs such as, colchicine, sulphasalazine, dapsone, and topical steroid are advocated for in the treatment of DPU, most if not all are unsatisfactory in relieving symptoms. Even a second generation antihistamine, ketotifen, was unable to efficiently and satisfactorily relieve symptoms of DPU
References
^ Dawn, G.; Urcelay, M.; Ah-Weng, A.; O'Neill, S.M.; Douglas, W.S. (2003). "Effect of high-dose intravenous immunoglobulin in delayed pressure urticaria". British Journal of Dermatology. 149 (4). Oxford University Press: 836–840. doi:10.1046/j.1365-2133.2003.05486.x. ISSN0007-0963. PMID14616377.
