Protein domain
In molecular biology, the EAL domain is a conserved protein domain . It is found in diverse bacterial signalling proteins . It is named EAL after its conserved residues . The EAL domain may function as a diguanylate phosphodiesterase . The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site .
References
Galperin MY, Nikolskaya AN, Koonin EV (September 2001). "Novel domains of the prokaryotic two-component signal transduction systems" . FEMS Microbiol. Lett . 203 (1): 11–21. doi :10.1016/S0378-1097(01)00326-3 . PMID 11557134 .
This article incorporates text from the public domain Pfam and InterPro : IPR001633
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EAL domain
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