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Fluorexetamine

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Chemical compound Not to be confused with fluoxetine. Pharmaceutical compound
Fluorexetamine
Legal status
Legal status
Identifiers
IUPAC name
  • 2-(ethylamino)-2-(3-fluorophenyl)cyclohexan-1-one
PubChem CID
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H18FNO
Molar mass235.302 g·mol
3D model (JSmol)
SMILES
  • CCNC1(CCCCC1=O)c1cccc(F)c1
InChI
  • InChI=1S/C14H18FNO/c1-2-16-14(9-4-3-8-13(14)17)11-6-5-7-12(15)10-11/h5-7,10,16H,2-4,8-9H2,1H3
  • Key:FCETYWCLCUZFJI-UHFFFAOYSA-N

Fluorexetamine (3'-Fluoro-2-oxo-PCE, 3-FXE) is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects. It has reportedly been sold over the internet since around 2017, though has remained relatively uncommon.

In April 2023 it was revealed by DrugsData.org that all their previously analyzed samples of fluorexetamine actually contained 2'-Fluoro-2-oxo-PCE (2-FXE, also known as CanKet) rather than 3'-Fluoro-2-oxo PCE (3-FXE). This was confirmed by a newly available reference standard for 2-FXE. Similar misidentification may have occurred in other laboratories.

See also

References

  1. Wallach J, Brandt SD (2018). "1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances". Handbook of Experimental Pharmacology. 252: 305–352. doi:10.1007/164_2018_148. ISBN 978-3-030-10560-0. PMID 30196446.
  2. Erowid, DrugsData org /. "DrugsData.org (was EcstasyData): Test Details : Result #15191 - White Crystals, 15191". www.drugsdata.org. Retrieved 2023-12-02.


Glutamate receptor modulators
Ionotropic glutamate receptor modulators
AMPARTooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
KARTooltip Kainate receptor
NMDARTooltip N-Methyl-D-aspartate receptor
Metabotropic glutamate receptor modulators
Group I
mGluR1Tooltip Metabotropic glutamate receptor 1
mGluR5Tooltip Metabotropic glutamate receptor 5
Group II
mGluR2Tooltip Metabotropic glutamate receptor 2
mGluR3Tooltip Metabotropic glutamate receptor 3
Group III
mGluR4Tooltip Metabotropic glutamate receptor 4
mGluR6Tooltip Metabotropic glutamate receptor 6
mGluR7Tooltip Metabotropic glutamate receptor 7
mGluR8Tooltip Metabotropic glutamate receptor 8
See also: Receptor/signaling modulatorsIonotropic glutamate receptor modulatorsGlutamate metabolism/transport modulators


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