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HIE-124

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Chemical compound Pharmaceutical compound

HIE-124
Identifiers

IUPAC name Ethyl 8-oxo-6,7-dihydro-5H-thiazolodiazepine-3-carboxylate
CAS Number	805326-00-5
PubChem CID	11447815
ChemSpider	9622668
UNII	JS6A6EQZ44
ChEMBL	ChEMBL450014
Chemical and physical data
Formula	C₁₀H₁₂N₂O₃S
Molar mass	240.28 g·mol
3D model (JSmol)	Interactive image
SMILES O=C(C1=CSC(N1CCC2)=NC2=O)OCC
InChI InChI=1S/C10H12N2O3S/c1-2-15-9(14)7-6-16-10-11-8(13)4-3-5-12(7)10/h6H,2-5H2,1H3 Key:UXGPDPNGDCOQBY-UHFFFAOYSA-N

HIE-124 is an investigational nonbenzodiazepine drug being researched for its short acting hypnotic effects.

References

Kadi A, El-Kashef H, Abdel-Aziz A, Hassan G, Tettey J, Grant M, Lehmann J, El-Subbagh H (February 2008). "Synthesis, ultra-short acting hypnotic activity, and metabolic profile of ethyl 8-oxo-5,6,7,8-tetrahydro-thiazolo diazepin-3-carboxylate (HIE-124)". Archiv der Pharmazie. 341 (2): 81–89. doi:10.1002/ardp.200700132. PMID 18214840. S2CID 12263886.

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