 | This article needs editing to comply with Misplaced Pages's Manual of Style. In particular, it has problems with not using MEDMOS. Please help improve the content. (July 2018) (Learn how and when to remove this message) |
| Hepatosplenomegaly | |
|---|---|
| Specialty | Gastroenterology  |
Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly). Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease. Systemic venous hypertension can also increase the risk for developing hepatosplenomegaly, which may be seen in those patients with right-sided heart failure.
Common causes
- Infection:
- Hematologic diseases:
- Metabolic disease:
- Chronic liver disease and portal hypertension:
- Amyloidosis
- Acromegaly
- Systemic lupus erythematosus
- Sarcoidosis
- Human African trypanosomiasis
- Drug abuse
- Obesity
Rare disorders
Are the following:
- Lipoproteinlipase deficiency
- Multiple sulfatase deficiency
- Osteopetrosis
- Adult-onset Still's disease (AOSD)
References
- ^ medcyclopaedia: Hepatosplenomegaly Retrieved on Nov 23, 2009
- ^ GPNotebook: hepatosplenomegaly Retrieved on Nov 23, 2009
- Xavier, Mariana (2010). "Pathogenesis of Brucella spp". The Open Veterinary Science Journal. 4: 109–118. doi:10.2174/1874318801004010109.
- "Typhoid & Paratyphoid Fever - Chapter 3 - 2016 Yellow Book - Travelers' Health - CDC".
- "Niemann-Pick disease". Genetics Home Reference. Retrieved 18 Sep 2020.
External links
| Classification | D |
|---|---|
| External resources |
| Signs and symptoms relating to the human digestive system or abdomen | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gastrointestinal tract |
| ||||||||
| Accessory | |||||||||
| Defecation | |||||||||
| Abdomen |
| ||||||||
| Hernia | |||||||||
| Other | |||||||||
 | This medical sign article is a stub. You can help Misplaced Pages by expanding it. |