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Non-Langerhans cell histiocytosis, also known as rare histiocytoses, comprise all histiocyte, macrophage, and dendritic cell proliferative disorders that are not categorized as hemophagocytic lymphohistiocytosis (HLH) or Langerhans cell histiocytosis (LCH).

The spectrum of non-langerhans cell histiocytoses include:

• Benign cephalic histiocytosis
• Generalized eruptive histiocytoma
• Indeterminate cell histiocytosis
• Juvenile xanthogranuloma
• Progressive nodular histiocytoma
• Necrobiotic xanthogranuloma
• (Giant Cell) Reticulohistiocytoma
• Multicentric reticulohistiocytosis
• Rosai–Dorfman disease
• Xanthoma disseminatum
• Kikuchi disease
• Erdheim–Chester disease.

References

1. Classen, C.; Minkov, M.; Lehrnbecher, T. (November 15, 2016). "The Non-Langerhans Cell Histiocytoses (Rare Histiocytoses) – Clinical Aspects and Therapeutic Approaches". Klinische Pädiatrie (in German). 228 (6/07). Georg Thieme Verlag KG: 294–306. doi:10.1055/s-0042-109713. ISSN 0300-8630. PMID 27846659. S2CID 22814976.
2. Rao RN, Chang CC, Uysal N, Presberg K, Shidham VB, Tomashefski JF (February 2005). "Fulminant multisystem non-langerhans cell histiocytic proliferation with hemophagocytosis: a variant form of Erdheim-Chester disease". Arch. Pathol. Lab. Med. 129 (2): e39–43. doi:10.5858/2005-129-e39-FMNCHP. PMID 15679446.

Further reading

• Weitzman, Sheila; Jaffe, Ronald (2005). "Uncommon histiocytic disorders: The non-Langerhans cell histiocytoses". Pediatric Blood & Cancer. 45 (3): 256–264. doi:10.1002/pbc.20246. ISSN 1545-5009. PMID 15547923. S2CID 25621667.
• Froehlich, Stephan J.; Lackerbauer, Carlo A.; Rudolph, Guenter; Rémi, Jan; Noachtar, Soheyl; Heppt, Werner J.; Cryer, Annette; Zenner, Hans-Peter; Niller, Hans Helmut; Schwarzmann, Fritz; Wolf, Hans; Frieling, Thomas; Leung, Alexander K. C.; Wallgren-Pettersson, Carina; Goebel, Hans H.; Jouret, François; Devuyst, Olivier; Attanasio, Massimo; Hildebrandt, Friedhelm; Jha, Vivekanand; Chugh, Kirpal S.; Marinaki, Anthony M.; Simmonds, H. Anne; Zhou, Xiaoyan; Frohlich, Edward D.; Tesar, Vladimir; Jalanko, Hannu; Oji, Vinzenz; Traupe, Heiko; Danek, Adrian; Angelini, Corrado; Kaufmann, Dieter; Kaufmann, Dieter; Weller, Michael; Kornhuber, Johannes; Vincent, Angela; Newsom-Davis, John; Mole, Sara; Williams, Ruth; Baets, Jonathan; Hanemann, C. Oliver; Jonghe, Peter; Holt, Ian; Klopstock, Thomas; Zeviani, Massimo; Ley, Klaus; Smith, Emily; Shiohara, Masaaki; Leung, Alexander K. C.; Robson, William Lane M.; Brokalaki, Eirini I.; Grabbe, Stephan; Loquai, Carmen; Nohr, Donatus; Nohr, Donatus; Gallinat, Jürgen; Schuchman, Edward H.; Desnick, Robert J.; Zeitz, Christina; Mizutani, Shuki; Orange, Jordan S.; Weiss, Jeffrey P.; Blaivas, Jerry G.; Robson, William Lane M.; Leung, Alexander K. C.; Ma, Lucia K.; Ma, Patrick T. S.; Leung, Alexander K. C.; Schwarz, Peter E. H.; Li, Jiang; LeRoith, Derek; Kure, Shigeo; Tada, Keiya; Utikal, Jochen; Gratchev, Alexei; Goerdt, Sergij; Senzolo, Marco; Piovesana, Elena; Okolicsanyi, Lajos; Burroughs, Andrew K.; Sistermans, Erik A.; Engel, Jutta; Fischer, M. Dominik; Berger, Wolfgang; Tozzi, Maria Grazia; Micheli, Vanna; Leung, Alexander K. C.; Robson, William Lane M. (2009). "Non-Langerhans' Cell Histiocytoses". Encyclopedia of Molecular Mechanisms of Disease. Berlin, Heidelberg: Springer Berlin Heidelberg. doi:10.1007/978-3-540-29676-8_1296. ISBN 978-3-540-67136-7.

External links

• Monocyte- and macrophage-related cutaneous conditions
• Histiocytosis