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IMP4
Identifiers
Aliases	IMP4, BXDC4, IMP4 homolog, U3 small nucleolar ribonucleoprotein, U3 small nucleolar ribonucleoprotein, IMP U3 small nucleolar ribonucleoprotein 4
External IDs	OMIM: 612981; MGI: 106572; HomoloGene: 68891; GeneCards: IMP4; OMA:IMP4 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q21.1 Start 130,342,877 bp End 130,347,967 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 B|1 13.22 cM Start 34,478,932 bp End 34,488,437 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas gastrocnemius muscle body of stomach right lobe of liver muscle of thigh mucosa of transverse colon left coronary artery prefrontal cortex granulocyte apex of heart Top expressed in zygote yolk sac primary oocyte morula morula embryo epiblast embryo right kidney secondary oocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding rRNA primary transcript binding snoRNA binding Cellular component small-subunit processome nucleolus nucleus nucleoplasm fibrillar center preribosome Mpp10 complex Biological process ribosome biogenesis rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 92856 27993 Ensembl ENSG00000136718 ENSMUSG00000026127 UniProt Q96G21 Q8VHZ7 RefSeq (mRNA) NM_033416 NM_001320304 NM_001320305 NM_001320306 NM_001320307 NM_001320309 NM_001320310 NM_001320311 NM_001371725 NM_001371726 NM_001371728 NM_001371730 NM_001371731 NM_001371732 NM_001371733 NM_001371734 NM_178601 RefSeq (protein) NP_001307233 NP_001307234 NP_001307235 NP_001307236 NP_001307238 NP_001307239 NP_001307240 NP_219484 NP_001358654 NP_001358655 NP_001358657 NP_001358659 NP_001358660 NP_001358661 NP_001358662 NP_001358663 NP_848716 Location (UCSC) Chr 2: 130.34 – 130.35 Mb Chr 1: 34.48 – 34.49 Mb PubMed search
Wikidata
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U3 small nucleolar ribonucleoprotein protein IMP4 is a protein that in humans is encoded by the IMP4 gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000136718 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000026127 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
6. Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
7. "Entrez Gene: IMP4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)".

Further reading

• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Granneman S, Gallagher JE, Vogelzangs J, et al. (2003). "The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes". Nucleic Acids Res. 31 (7): 1877–87. doi:10.1093/nar/gkg300. PMC 152815. PMID 12655004.
• Leary DJ, Terns MP, Huang S (2004). "Components of U3 snoRNA-containing complexes shuttle between nuclei and the cytoplasm and differentially localize in nucleoli: implications for assembly and function". Mol. Biol. Cell. 15 (1): 281–93. doi:10.1091/mbc.E03-06-0363. PMC 307547. PMID 14565981.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.

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