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JAKMIP2
Identifiers
Aliases	JAKMIP2, JAMIP2, NECC1, janus kinase and microtubule interacting protein 2
External IDs	OMIM: 611197; MGI: 1923467; HomoloGene: 8866; GeneCards: JAKMIP2; OMA:JAKMIP2 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) Band 5q32 Start 147,585,438 bp End 147,782,775 bp
Gene location (Mouse) Chr. Chromosome 18 (mouse) Band 18|18 B3 Start 43,664,472 bp End 43,820,838 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone sural nerve middle temporal gyrus ganglionic eminence corpus callosum dorsal motor nucleus of vagus nerve entorhinal cortex prefrontal cortex postcentral gyrus Brodmann area 46 Top expressed in habenula piriform cortex lobe of cerebellum mammillary body anterior amygdaloid area ventromedial nucleus subiculum cerebellar vermis lateral hypothalamus primary motor cortex More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 9832 76217 Ensembl ENSG00000176049 ENSMUSG00000024502 UniProt Q96AA8 D3YXK0 RefSeq (mRNA) NM_014790 NM_001270934 NM_001270941 NM_001282282 NM_001163637 RefSeq (protein) NP_001257863 NP_001257870 NP_001269211 NP_055605 NP_001157109 Location (UCSC) Chr 5: 147.59 – 147.78 Mb Chr 18: 43.66 – 43.82 Mb PubMed search
Wikidata
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Janus kinase and microtubule interacting protein 2 is a protein that in humans is encoded by the JAKMIP2 gene.

Function

The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000176049 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000024502 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Janus kinase and microtubule interacting protein 2". Retrieved 2017-05-31.

Further reading

• Cruz-Garcia D, Vazquez-Martinez R, Peinado JR, Anouar Y, Tonon MC, Vaudry H, Castaño JP, Malagon MM (2007). "Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins". FEBS Lett. 581 (17): 3149–56. doi:10.1016/j.febslet.2007.06.002. PMID 17572408. S2CID 29349416.
• Koskinen LL, Einarsdottir E, Korponay-Szabo IR, Kurppa K, Kaukinen K, Sistonen P, Pocsai Z, Széles G, Adány R, Mäki M, Kere J, Saavalainen P (2009). "Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations". Tissue Antigens. 74 (5): 408–16. doi:10.1111/j.1399-0039.2009.01359.x. PMID 19845895.
• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.

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