| KCNK17 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | KCNK17, K2p17.1, TALK-2, TALK2, TASK-4, TASK4, potassium two pore domain channel subfamily K member 17 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 607370; HomoloGene: 88928; GeneCards: KCNK17; OMA:KCNK17 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Potassium channel subfamily K member 17 is a protein that in humans is encoded by the KCNK17 gene.
This gene encodes K2P17.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel, primarily expressed in the pancreas, is activated at alkaline pH.
See also
References
- ^ GRCh38: Ensembl release 89: ENSG00000124780 – Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106. S2CID 7356601.
- ^ "Entrez Gene: KCNK17 potassium channel, subfamily K, member 17".
Further reading
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Girard C, Duprat F, Terrenoire C, et al. (2001). "Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels". Biochem. Biophys. Res. Commun. 282 (1): 249–56. doi:10.1006/bbrc.2001.4562. PMID 11263999.
- Decher N, Maier M, Dittrich W, et al. (2001). "Characterization of TASK-4, a novel member of the pH-sensitive, two-pore domain potassium channel family". FEBS Lett. 492 (1–2): 84–9. Bibcode:2001FEBSL.492...84D. doi:10.1016/S0014-5793(01)02222-0. PMID 11248242. S2CID 23620127.
External links
- KCNK17+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
| Membrane transport protein: ion channels (TC 1A) | |||||||||||||||||
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