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Kelch-like protein 1

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Protein-coding gene in the species Homo sapiens
KLHL1
Identifiers
AliasesKLHL1, MRP2, kelch like family member 1
External IDsOMIM: 605332; MGI: 2136335; HomoloGene: 56903; GeneCards: KLHL1; OMA:KLHL1 - orthologs
Gene location (Human)
Chromosome 13 (human)
Chr.Chromosome 13 (human)
Chromosome 13 (human)Genomic location for KLHL1Genomic location for KLHL1
Band13q21.33Start69,700,594 bp
End70,108,493 bp
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)
Chromosome 14 (mouse)Genomic location for KLHL1Genomic location for KLHL1
Band14|14 E2.1Start96,340,172 bp
End96,756,538 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • pars reticulata

  • pars compacta

  • testicle

  • superior vestibular nucleus

  • ventral tegmental area

  • Pons

  • Hypothalamus

  • islet of Langerhans

  • ganglionic eminence

  • prefrontal cortex
Top expressed in
  • ventral tegmental area

  • substantia nigra

  • lumbar subsegment of spinal cord

  • lateral hypothalamus

  • habenula

  • ventromedial nucleus

  • mammillary body

  • supraoptic nucleus

  • central gray substance of midbrain

  • medial vestibular nucleus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

57626

93688

Ensembl

ENSG00000150361

ENSMUSG00000022076

UniProt

Q9NR64

Q9JI74

RefSeq (mRNA)

NM_020866
NM_001286725

NM_053105

RefSeq (protein)

NP_001273654
NP_065917

NP_444335

Location (UCSC)Chr 13: 69.7 – 70.11 MbChr 14: 96.34 – 96.76 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Kelch-like protein 1 is a protein that in humans is encoded by the KLHL1 gene.


References

  1. ^ GRCh38: Ensembl release 89: ENSG00000150361Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000022076Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nemes JP, Benzow KA, Moseley ML, Ranum LP, Koob MD (Sep 2000). "The SCA8 transcript is an antisense RNA to a brain-specific transcript encoding a novel actin-binding protein (KLHL1)". Hum Mol Genet. 9 (10): 1543–51. doi:10.1093/hmg/9.10.1543. PMID 10888605.
  6. "Entrez Gene: KLHL1 kelch-like 1 (Drosophila)".

Further reading


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