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L-165041

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Chemical compound Pharmaceutical compound
L-165041
Clinical data
Pregnancy
category
  • N/A
Legal status
Legal status
  • Investigational
Identifiers
IUPAC name
  • phenoxy]acetic acid
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H26O7
Molar mass402.443 g·mol
3D model (JSmol)
SMILES
  • CCCc1c(ccc(c1O)C(=O)C)OCCCOc2ccc(cc2)OCC(=O)O
InChI
  • InChI=1S/C22H26O7/c1-3-5-19-20(11-10-18(15(2)23)22(19)26)28-13-4-12-27-16-6-8-17(9-7-16)29-14-21(24)25/h6-11,26H,3-5,12-14H2,1-2H3,(H,24,25)
  • Key:HBBVCKCCQCQCTJ-UHFFFAOYSA-N

L-165041 is a phenyloxyacetate PPARδ receptor agonist. It is less potent and PPARδ selective than GW 501516.

See also

References

  1. Iwashita A, Muramatsu Y, Yamazaki T, Muramoto M, Kita Y, Yamazaki S, et al. (March 2007). "Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo". The Journal of Pharmacology and Experimental Therapeutics. 320 (3): 1087–96. doi:10.1124/jpet.106.115758. PMID 17167170. S2CID 9595370.
  2. Atta-ur-Rahman, Reitz AB (2005). Frontiers in Medicinal Chemistry, Volume 2. Bentham Science Publishers. pp. 244–. ISBN 978-1-608-05205-9. Retrieved 2 April 2013.
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