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L-Fuculokinase

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Class of enzymes
L-Fuculokinase
Identifiers
EC no.2.7.1.51
CAS no.9026-64-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

L-Fuculokinase (EC 2.7.1.51) is an enzyme that catalyzes the chemical reaction

ATP + L-fuculose (L-fuculokinase) ⇌ ADP + L-fuculose-1-phosphate

Thus, the two substrates of this enzyme are ATP and L-fuculose, whereas its two products are ADP and L-fuculose-1-phosphate.

The gene name used for the gene that encodes L-fuculokinase is fucK.

L-Fuculokinase belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:L-fuculose 1-phosphotransferase. Other names in common use include L-fuculokinase (phosphorylating), and L-fuculose kinase. This enzyme participates in fructose and mannose metabolism.

References

  1. Heath EC, Ghalambor MA (1962). "The metabolism of L-fucose. I. The purification and properties of L-fuculose kinase". J. Biol. Chem. 237: 2423–6. PMID 13905785.
  2. "NCBI gene database entry for E. coli O157:H7 fucK". National Center for Biotechnology Information. 2010-02-07. Retrieved 20 February 2010.
Transferases: phosphorus-containing groups (EC 2.7)
2.7.1-2.7.4:
phosphotransferase/kinase
(PO4)
2.7.1: OH acceptor
2.7.2: COOH acceptor
2.7.3: N acceptor
2.7.4: PO4 acceptor
2.7.6: diphosphotransferase
(P2O7)
2.7.7: nucleotidyltransferase
(PO4-nucleoside)
Polymerase
DNA polymerase
DNA-directed DNA polymerase
I/A
γ
θ
ν
T7
Taq
II/B
α
δ
ε
ζ
Pfu
III/C
IV/X
β
λ
μ
TDT
V/Y
η
ι
κ
RNA-directed DNA polymerase
Reverse transcriptase
Telomerase
RNA polymerase
Template-directed
RNA polymerase I
II
III
IV
V
ssRNAP
POLRMT
Primase
1
2
PrimPol
RNA-dependent RNA polymerase
Polyadenylation
PAP
PNPase
Phosphorolytic
3' to 5' exoribonuclease
Nucleotidyltransferase
Guanylyltransferase
Other
2.7.8: miscellaneous
Phosphatidyltransferases
Glycosyl-1-phosphotransferase
2.7.10-2.7.13: protein kinase
(PO4; protein acceptor)
2.7.10: protein-tyrosine
2.7.11: protein-serine/threonine
2.7.12: protein-dual-specificity
2.7.13: protein-histidine
Enzymes
Activity
Regulation
Classification
Kinetics
Types
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