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Lenampicillin

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Chemical compound Pharmaceutical compound
Lenampicillin
Clinical data
Trade namesTakacillin, Varacillin
Other namesKBT-1585
Legal status
Legal status
  • Rx in Japan
Identifiers
IUPAC name
  • (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicycloheptane-2-carboxylate
CAS Number
PubChem CID
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC21H23N3O7S
Molar mass461.49 g·mol

Lenampicillin is an antibiotic drug of the penicillin class. It is a produg of ampicillin; after oral administration of lenampicillin, ampicillin is rapidly formed.

Lenampicillin inhibits bacterial penicillin binding proteins (transpeptidase) and is effective against a wide range of bacterial infections.

Lenampicillin was developed in Japan and has been marketed there.

References

  1. Saito A, Nakashima M (May 1986). "Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers". Antimicrobial Agents and Chemotherapy. 29 (5): 948–950. doi:10.1128/aac.29.5.948. PMC 284190. PMID 3729355.
  2. ^ "Lenampicillin". InxightDrugs. National Center for Advancing Translational Sciences.
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