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Mannosylfructose-phosphate synthase

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Class of enzymes
Mannosylfructose-phosphate synthase
Identifiers
EC no.2.4.1.246
CAS no.92480-04-1 (not distinguished from EC 2.4.1.167)
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

Mannosylfructose-phosphate synthase (EC 2.4.1.246, mannosylfructose-6-phosphate synthase, MFPS) is an enzyme with systematic name GDP-mannose:D-fructose-6-phosphate 2-alpha-D-mannosyltransferase. This enzyme catalyses the following chemical reaction

GDP-mannose + D-fructose 6-phosphate {\displaystyle \rightleftharpoons } GDP + beta-D-fructofuranosyl-alpha-D-mannopyranoside 6F-phosphate

This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg or Mn for activity.

References

  1. Torres LL, Salerno GL (September 2007). "A metabolic pathway leading to mannosylfructose biosynthesis in Agrobacterium tumefaciens uncovers a family of mannosyltransferases". Proceedings of the National Academy of Sciences of the United States of America. 104 (36): 14318–23. doi:10.1073/pnas.0706709104. PMC 1964871. PMID 17728402.

External links

Transferases: glycosyltransferases (EC 2.4)
2.4.1: Hexosyl-
transferases
Glucosyl-
Galactosyl-
Glucuronosyl-
Fucosyl-
Mannosyl-
2.4.2: Pentosyl-
transferases
Ribose
ADP-ribosyltransferase
Phosphoribosyltransferase
Other
Other
2.4.99: Sialyl
transferases
Enzymes
Activity
Regulation
Classification
Kinetics
Types
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