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Miotine

Names
IUPAC name phenyl] N-methylcarbamate
Other names AR-28 T-1843
Identifiers
CAS Number	4464-16-8
3D model (JSmol)	Interactive image
ChemSpider	41955
KEGG	C11763
PubChem CID	46093
UNII	9Z3ZT09RRU
CompTox Dashboard (EPA)	DTXSID10275489
InChI InChI=1S/C12H18N2O2/c1-9(14(3)4)10-6-5-7-11(8-10)16-12(15)13-2/h5-9H,1-4H3,(H,13,15)Key: KQOUPMYYRQWZLI-UHFFFAOYSA-N InChI=1/C12H18N2O2/c1-9(14(3)4)10-6-5-7-11(8-10)16-12(15)13-2/h5-9H,1-4H3,(H,13,15)Key: KQOUPMYYRQWZLI-UHFFFAOYAX
SMILES CC(C1=CC(=CC=C1)OC(=O)NC)N(C)C
Properties
Chemical formula	C12H18N2O2
Molar mass	222.288 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). N verify (what is  ?) Infobox references

Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.

Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.

See also

• Neostigmine
• T-1123
• TL-1238
• TMTFA

References

1. ^ Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
2. "Archived copy" (PDF). Archived from the original (PDF) on 2009-05-09. Retrieved 2008-01-04.{{cite web}}: CS1 maint: archived copy as title (link)
3. "An introduction to drugs,their action and discovery" (PDF).

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