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MUC20
Identifiers
Aliases	MUC20, MUC-20, mucin 20, cell surface associated
External IDs	OMIM: 610360; MGI: 2385039; HomoloGene: 17135; GeneCards: MUC20; OMA:MUC20 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3q29 Start 195,720,884 bp End 195,741,123 bp
Gene location (Mouse) Chr. Chromosome 16 (mouse) Band 16|16 B3 Start 32,597,793 bp End 32,617,805 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube olfactory zone of nasal mucosa gallbladder sural nerve palpebral conjunctiva minor salivary glands rectum mucosa of transverse colon anterior pituitary gastric mucosa Top expressed in lumbar subsegment of spinal cord zygote conjunctival fornix right kidney right ventricle secondary oocyte cornea tibiofemoral joint right lung primary oocyte More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 200958 224116 Ensembl ENSG00000274843 ENSG00000281630 ENSG00000277753 ENSG00000275501 ENSG00000275430 ENSG00000276583 ENSG00000278114 ENSG00000176945 ENSMUSG00000035638 UniProt Q8N307 Q8BUE7 RefSeq (mRNA) NM_152673 NM_001098516 NM_001282506 NM_001291833 NM_020790 NM_001145874 NM_146071 RefSeq (protein) NP_001269435 NP_001278762 NP_065841 NP_689886 NP_001139346 NP_666183 Location (UCSC) Chr 3: 195.72 – 195.74 Mb Chr 16: 32.6 – 32.62 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Mucin-20 is a protein that in humans is encoded by the MUC20 gene.

References

1. ^ ENSG00000281630, ENSG00000277753, ENSG00000275501, ENSG00000275430, ENSG00000276583, ENSG00000278114, ENSG00000176945 GRCh38: Ensembl release 89: ENSG00000274843, ENSG00000281630, ENSG00000277753, ENSG00000275501, ENSG00000275430, ENSG00000276583, ENSG00000278114, ENSG00000176945 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000035638 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Higuchi T, Orita T, Nakanishi S, Katsuya K, Watanabe H, Yamasaki Y, Waga I, Nanayama T, Yamamoto Y, Munger W, Sun HW, Falk RJ, Jennette JC, Alcorta DA, Li H, Yamamoto T, Saito Y, Nakamura M (Jan 2004). "Molecular cloning, genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney". J Biol Chem. 279 (3): 1968–79. doi:10.1074/jbc.M304558200. PMID 14565953.
6. "Entrez Gene: MUC20 mucin 20, cell surface associated".

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Higuchi T, Orita T, Katsuya K, et al. (2004). "MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met". Mol. Cell. Biol. 24 (17): 7456–68. doi:10.1128/MCB.24.17.7456-7468.2004. PMC 506992. PMID 15314156.
• Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
• Li G, Zhang H, Lv J, et al. (2006). "Tandem repeats polymorphism of MUC20 is an independent factor for the progression of immunoglobulin A nephropathy". Am. J. Nephrol. 26 (1): 43–9. doi:10.1159/000091785. PMID 16508246. S2CID 38456730.

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