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Hepatitis C virus nonstructural protein 4B

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HCV genome

Nonstructural protein 4B (NS4B) is a viral protein found in the hepatitis C virus. It has mass of 27 kDa and probably involved in process of intracellular membrane structure formation to allow virus replication.

References

  1. Beld M, Penning M, van Putten M, et al. (October 1998). "Hepatitis C virus serotype-specific core and NS4 antibodies in injecting drug users participating in the Amsterdam cohort studies". J. Clin. Microbiol. 36 (10): 3002–6. doi:10.1128/JCM.36.10.3002-3006.1998. PMC 105101. PMID 9738057.
  2. Ella H Sklan and Jeffrey S Glenn. Chapter 8. HCV NS4B: From Obscurity to Central Stage in "Hepatitis C Viruses: Genomes and Molecular Biology." / Tan SL. — Norfolk: Horizon Bioscience, 2006.
Viral proteins (early and late)
DNA
linear ds-DNA
(Duplodnaviria,
Varidnaviria)
Herpes simplex
VSPs:
capsid:
VNPs:
Vaccinia
VNPs:
Adenoviridae
VNPs:
circular ds-DNA
(Duplodnaviria,
Varidnaviria?)
Epstein–Barr
VSPs:
VNPs:
ncRNA:
Baculoviridae
VNPs:
other
(Riboviria,
Monodnaviria)
Polyomaviridae
(SV40, MPyV, MCPyV, HaPyV)
(non-enveloped circular ds-DNA)
VSPs:
capsid:
VNPs:
oncoprotein:
Hepatitis B
(circular partially ds-DNA)
VSPs:
  • HBsAg
  • HBcAg
    • VNPs:
    RNA
    ds-RNA
    (Riboviria)
    Rotavirus
    (Duplornaviricota)
    VNPs:
    Rhinov., Polio, Hep A,
    etc. (Pisuviricota)
    VNPs:
    ss-RNA
    positive-sense
    (Riboviria)
    Hepatitis C
    (Kitrinoviricota)
    VSPs:
    VNPs:
    SARS-CoV-2
    (Pisuviricota)
    VSPs:
    VNPs:
    ss-RNA
    negative-sense
    (Negarnaviricota)
    Influenza virus
    VSPs:
    capsid:
    glycoprotein:
    VNPs:
    Parainfluenza
    VSPs:
    glycoprotein:
    Mumps
    VSPs:
    glycoprotein:
    Measles
    VSPs:
    glycoprotein:
    RSV
    VSPs:
    glycoprotein:
    Zaire ebolavirus
    VSPs:
    capsid:
    Indiana vesiculovirus
    VSPs:
    capsid:
    RT
    Structure and genome of HIV
    VSPs:
    VRAPs:
    Multiple
    Fusion protein
    oncoprotein:
  • Gag-onc fusion protein


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