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Oleclumab

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Monoclonal antibody Pharmaceutical compound
Oleclumab
Monoclonal antibody
Type?
SourceHuman
Target5'-nucleotidase NT5E
Clinical data
Other namesMEDI9447
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6348H9826N1710O1998S40
Molar mass143350.81 g·mol

Oleclumab (INN; development code MEDI9447) is a human monoclonal antibody targeting the ectonucleotidase CD73 that was designed for the treatment of pancreatic and colorectal and other cancers.

This drug was developed by MedImmune/AstraZeneca.

References

  1. World Health Organization (2016). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 116" (PDF). WHO Drug Information. 30 (4).
  2. ClinicalTrial.gov for Oleclumab
  3. Statement On A Nonproprietary Name Adopted By The USAN Council - Oleclumab, American Medical Association.
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Monoclonal antibodies for the immune system
Immune system
Human
Mouse
Chimeric
Humanized

Immune activation: Dostarlimab
Other: Ibalizumab

Chimeric + humanized
Interleukin
Human
Humanized
Veterinary
Inflammatory lesions
Mouse
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