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PARP12

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Protein-coding gene in the species Homo sapiens
PARP12
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2PQF

Identifiers
AliasesPARP12, ARTD12, MST109, MSTP109, ZC3H1, ZC3HDC1, poly(ADP-ribose) polymerase family member 12
External IDsOMIM: 612481; MGI: 2143990; HomoloGene: 11236; GeneCards: PARP12; OMA:PARP12 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)
Chromosome 7 (human)Genomic location for PARP12Genomic location for PARP12
Band7q34Start140,023,749 bp
End140,062,951 bp
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)
Chromosome 6 (mouse)Genomic location for PARP12Genomic location for PARP12
Band6|6 B1Start39,063,344 bp
End39,095,283 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • granulocyte

  • right lung

  • upper lobe of left lung

  • monocyte

  • spleen

  • mucosa of ileum

  • mucosa of transverse colon

  • rectum

  • tibial nerve
Top expressed in
  • zygote

  • secondary oocyte

  • primary oocyte

  • intestinal villus

  • stroma of bone marrow

  • pineal gland

  • mucous cell of stomach

  • left colon

  • jejunum

  • ileum
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

64761

243771

Ensembl

ENSG00000059378

ENSMUSG00000038507

UniProt

Q9H0J9

Q8BZ20

RefSeq (mRNA)

NM_022750

NM_172893

RefSeq (protein)

NP_073587

NP_766481

Location (UCSC)Chr 7: 140.02 – 140.06 MbChr 6: 39.06 – 39.1 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Poly polymerase 12 is an enzyme that in humans is encoded by the PARP12 gene.


References

  1. ^ GRCh38: Ensembl release 89: ENSG00000059378Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000038507Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. Katoh M, Katoh M (Jul 2003). "Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31". Int J Oncol. 23 (2): 541–7. doi:10.3892/ijo.23.2.541. PMID 12851707.
  7. "Entrez Gene: PARP12 poly (ADP-ribose) polymerase family, member 12".

Further reading

PDB gallery
  • 2pqf: Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid 2pqf: Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid


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