Piericidin A - Misplaced Pages

Piericidin A
Names

Preferred IUPAC name 2--5,6-dimethoxy-3-methylpyridin-4(1H)-one
Other names Piericidin A1, AR-054
Identifiers
CAS Number	2738-64-9
3D model (JSmol)	Interactive image
ChEBI	CHEBI:138511
ChemSpider	4942360
ECHA InfoCard	100.162.726
MeSH	Piericidin+A
PubChem CID	6437838
UNII	8VT513UJ9R
CompTox Dashboard (EPA)	DTXSID80880044
InChI InChI=1S/C25H37NO4/c1-9-18(4)22(27)19(5)15-17(3)12-10-11-16(2)13-14-21-20(6)23(28)24(29-7)25(26-21)30-8/h9-10,12-13,15,19,22,27H,11,14H2,1-8H3,(H,26,28)/b12-10+,16-13+,17-15+,18-9+/t19-,22+/m1/s1Key: BBLGCDSLCDDALX-LKGBESRRSA-N
SMILES C/C=C(\C)/((C)/C=C(\C)/C=C/C/C(=C/Cc1c(c(=O)c(c(1)OC)OC)C)/C)O
Properties
Chemical formula	C₂₅H₃₇NO₄
Molar mass	415.574 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). N verify (what is ?) Infobox references

Chemical compound

Piericidin A is an antibiotic agent. It was discovered from Streptomyces mobaraensis. Being an inhibitor of NADH dehydrogenase, it inhibits electron transfer; its structure resembles that of the ubiquinone, therefore it competes with Q_B for binding sites in NADH dehydrogenase as well as photosystem II.

References

"MeSH Record of Piericidin A". U.S. National Library of Medicine, NIH. Retrieved 2018-05-22.

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