Piromidic acid - Misplaced Pages

Chemical compound Pharmaceutical compound

Piromidic acid
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	J01MB03 (WHO)
Identifiers
IUPAC name 8-Ethyl-5-oxo-2-pyrrolidin-1-yl-5,8-dihydropyridopyrimidine-6-carboxylic acid
CAS Number	19562-30-2
PubChem CID	4855
ChemSpider	4689
UNII	3I12WH4EWF
KEGG	D01431
ChEBI	CHEBI:32019
CompTox Dashboard (EPA)	DTXSID4045424
ECHA InfoCard	100.039.223
Chemical and physical data
Formula	C₁₄H₁₆N₄O₃
Molar mass	288.307 g·mol
3D model (JSmol)	Interactive image
SMILES CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCCC3)C(=O)O
InChI InChI=1S/C14H16N4O3/c1-2-17-8-10(13(20)21)11(19)9-7-15-14(16-12(9)17)18-5-3-4-6-18/h7-8H,2-6H2,1H3,(H,20,21) Key:RCIMBBZXSXFZBV-UHFFFAOYSA-N

Piromidic acid is a quinolone antibiotic.

References

Minami S, Shono T, Matsumoto JI (1971). "Pyrido pyrimidine Antibacterial Agents. II. Piromidic Acid and Related Compounds". Chemical and Pharmaceutical Bulletin. 19 (7): 1426–1432. doi:10.1248/cpb.19.1426.

Antifolates
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)

Short-acting	Sulfaisodimidine Sulfamethizole Sulfadimidine (Sulfamethazine, Sulfadimerazine, Sulfadimezine) Sulfapyridine (Sulfasalazine) Sulfafurazole (Acetyl sulfisoxazole) Sulfanilamide Prontosil Sulfathiazole (Phthalylsulfathiazole, Succinylsulfathiazole) Sulfathiourea
Intermediate-acting	Sulfamethoxazole Sulfadiazine Sulfamoxole
Long-acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone
Other/ungrouped	Mafenide Sulfacetamide Sulfaclozine Sulfadicramide Sulfaguanidine Sulfametrole Sulfanitran

Combinations

Other DHPS inhibitors

Quinolones
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)

2nd generation	Ciprofloxacin Ofloxacin Enoxacin Fleroxacin Lomefloxacin Nadifloxacin/Levonadifloxacin/Alalevonadifloxacin Norfloxacin Pefloxacin Rufloxacin
3rd generation	Levofloxacin Balofloxacin Grepafloxacin Pazufloxacin Sparfloxacin Temafloxacin Tosufloxacin
4th generation	Besifloxacin Delafloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin Clinafloxacin Garenoxacin Prulifloxacin Sitafloxacin Trovafloxacin/Alatrofloxacin
Veterinary	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Newer non-fluorinated

Related (DG)

Nitroimidazole derivatives	Secnidazole

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin Rifabutin Rifapentine Rifaximin Rifalazil
Lipiarmycins	Fidaxomicin

This systemic antibiotic-related article is a stub. You can help Misplaced Pages by expanding it.