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The drug combination sulfacetamide/sulfur is a topical acne medication manufactured by Medicis under the trade name Plexion and also available under other trade names such as Clenia, Prascion, and Avar. It combines sodium sulfacetamide, a sulfonamide antibiotic, and sulfur, a keratolytic agent. It is available in four formulations: as a cleansing cloth, cleanser, topical suspension, and as a facial mask. The sulfacetamide inhibits the growth of the bacterium Cutibacterium acnes that is associated with acne, while sulfur facilitates the removal of dead skin cells to prevent clogged pores.

In 2022, it was the 300th most commonly prescribed medication in the United States, with more than 300,000 prescriptions.

References

1. Del Rosso JQ (January 2004). "Evaluating the role of topical therapies in the management of rosacea: focus on combination sodium sulfacetamide and sulfur formulations". Cutis. 73 (1 Suppl): 29–33. PMID 14959943.
2. "Plexion (sodium sulfacetamide 10% and sulfur 5%)". Medicis Inc. Retrieved 2 December 2008.
3. "Plexion Prescribing information" (PDF). Medicis. Retrieved 2 December 2008.
4. "The Top 300 of 2022". ClinCalc. Archived from the original on 30 August 2024. Retrieved 30 August 2024.
5. "Sulfacetamide; Sulfur Drug Usage Statistics, United States, 2013 - 2022". ClinCalc. Retrieved 30 August 2024.

• Medicine

• Anti-acne preparations
• Combination drugs