Polyamine oxidase (propane-1,3-diamine-forming)

Polyamine oxidase (propane-1,3-diamine-forming) (EC 1.5.3.14, MPAO, maize PAO) is an enzyme with systematic name spermidine:oxygen oxidoreductase (propane-1,3-diamine-forming). This enzyme catalyses the following chemical reaction

spermidine + O₂ + H₂O

\rightleftharpoons

propane-1,3-diamine + 4-aminobutanal + H₂O₂

The products of the reaction cannot be converted directly to other polyamines.

References

Tavladoraki P, Schininà ME, Cecconi F, Di Agostino S, Manera F, Rea G, Mariottini P, Federico R, Angelini R (April 1998). "Maize polyamine oxidase: primary structure from protein and cDNA sequencing". FEBS Letters. 426 (1): 62–6. doi:10.1016/S0014-5793(98)00311-1. PMID 9598979.
Federico R, Ercolini L, Laurenzi M, Angelini R (1996). "Oxidation of acetylpolyamines by maize polyamine oxidase". Phytochemistry. 43: 339–341. doi:10.1016/0031-9422(96)00316-0.

External links

Polyamine+oxidase+(propane-1,3-diamine-forming) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

v t e Oxidoreductases: CH-NH (EC 1.5)
1.5.1: NAD or NADP acceptor	Dihydrofolate reductase Saccharopine dehydrogenase Methylenetetrahydrofolate reductase
1.5.3: oxygen acceptor	Dihydrobenzophenanthridine oxidase Sarcosine oxidase Proline oxidase
1.5.5: quinone acceptor	Electron-transferring-flavoprotein dehydrogenase
1.5.99	Sarcosine dehydrogenase Cytokinin dehydrogenase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Portal:

Biology

Category:

EC 1.5.3