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Polythiazide

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Chemical compound Pharmaceutical compound
Polythiazide
Space-filling model of the polythiazide molecule
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa601101
ATC code
Identifiers
IUPAC name
  • 6-chloro-2-methyl-3-{methyl}-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.005.881 Edit this at Wikidata
Chemical and physical data
FormulaC11H13ClF3N3O4S3
Molar mass439.87 g·mol
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Polythiazide is a thiazide diuretic.

References

  1. O'Brien ET, MacKinnon J (October 1972). "Propranolol and polythiazide in treatment of hypertension". British Heart Journal. 34 (10): 1042–4. doi:10.1136/hrt.34.10.1042. PMC 458544. PMID 5086971.
  2. Monroy A, Plata C, Hebert SC, Gamba G (July 2000). "Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction". American Journal of Physiology. Renal Physiology. 279 (1): F161-9. doi:10.1152/ajprenal.2000.279.1.f161. PMID 10894798.
Symporter inhibitors
Na-Cl
Na-K-Cl
See also: Receptor/signaling modulators
Diuretics (C03)
Sulfonamides
(and etacrynic acid)
CA inhibitors (at PT)
Loop (Na-K-Cl at AL)
Thiazides (Na-Cl at DCT,
Calcium-sparing)
Thiazide-likes (primarily DCT)
Potassium-sparing (at CD)
ESC blockers
Aldosterone antagonists
Osmotic diuretics (PT, DL)
Vasopressin receptor inhibitors
(DCT and CD)
Other
Combination products
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