Misplaced Pages

This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these messages) This article is an orphan, as no other articles link to it. Please introduce links to this page from related articles; try the Find link tool for suggestions. (December 2021) This article relies excessively on references to primary sources. Please improve this article by adding secondary or tertiary sources. Find sources: "QueA RNA motif" – news · newspapers · books · scholar · JSTOR (November 2021) (Learn how and when to remove this message) (Learn how and when to remove this message)

queA
Consensus secondary structure and sequence conservation of queA RNA
Identifiers
Symbol	queA
Rfam	RF03093
Other data
RNA type	Gene; sRNA
SO	SO:0001263
PDB structures	PDBe

The queA RNA motif is a conserved RNA structure that was discovered by bioinformatics. queA motif RNAs have not yet (as of 2018) been found in any classified organism; they are known from metagenomic sequences.

All known queA RNAs are located upstream of queA genes, which encodes an enzyme to alter the chemical structure of a specific nucleotide within tRNAs. It is possible that queA RNAs function as cis-regulatory elements. PreQ₁ riboswitches are known that bind pre-queuosine1 and regulate genes that are related to queA. However, as the que RNA motif is not highly conserved and the queA gene itself is never known to be regulated by a preQ₁ riboswitch, it is not likely that queA RNAs correspond to riboswitches.

References

1. Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.

• Non-coding RNA