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Quinethazone

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Chemical compound Pharmaceutical compound
Quinethazone
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline-
    6-sulfonamide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.729 Edit this at Wikidata
Chemical and physical data
FormulaC10H12ClN3O3S
Molar mass289.73 g·mol
3D model (JSmol)
SMILES
  • O=S(=O)(c2c(Cl)cc1c(C(=O)NC(N1)CC)c2)N
InChI
  • InChI=1S/C10H12ClN3O3S/c1-2-9-13-7-4-6(11)8(18(12,16)17)3-5(7)10(15)14-9/h3-4,9,13H,2H2,1H3,(H,14,15)(H2,12,16,17)
  • Key:AGMMTXLNIQSRCG-UHFFFAOYSA-N
  (verify)

Quinethazone (INN, brand name Hydromox) is a thiazide-like diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.

References

  1. Sandler G (August 1964). "Quinethazone, a new oral diuretic". British Medical Journal. 2 (5404): 288–92. doi:10.1136/bmj.2.5404.288. PMC 1815620. PMID 14160213.


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