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RHOBTB3
Identifiers
Aliases	RHOBTB3, Rho related BTB domain containing 3
External IDs	OMIM: 607353; MGI: 1920546; HomoloGene: 8932; GeneCards: RHOBTB3; OMA:RHOBTB3 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) Band 5q15 Start 95,713,522 bp End 95,824,383 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 C1 Start 76,017,656 bp End 76,092,044 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibia retinal pigment epithelium parotid gland Achilles tendon globus pallidus internal globus pallidus external globus pallidus corpus epididymis placenta caput epididymis Top expressed in hand sciatic nerve otolith organ utricle seminal vesicula medial ganglionic eminence mandibular prominence maxillary prominence abdominal wall vestibular sensory epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding protein binding hydrolase activity ATP binding ATPase activity GTPase activity GTP binding protein kinase binding Cellular component cytoplasm Golgi apparatus extracellular exosome cytosol trans-Golgi network membrane plasma membrane cell cortex cell projection Biological process retrograde transport, endosome to Golgi vesicle-mediated transport male gonad development transport actin filament organization establishment or maintenance of cell polarity Rho protein signal transduction regulation of cell shape actin cytoskeleton organization regulation of actin cytoskeleton organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22836 73296 Ensembl ENSG00000164292 ENSMUSG00000021589 UniProt O94955 Q9CTN4 RefSeq (mRNA) NM_014899 NM_028493 RefSeq (protein) NP_055714 NP_082769 Location (UCSC) Chr 5: 95.71 – 95.82 Mb Chr 13: 76.02 – 76.09 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Rho-related BTB domain-containing protein 3 is a protein that in humans is encoded by the RHOBTB3 gene.

Function

RHOBTB3 is a member of the evolutionarily conserved RhoBTB subfamily of Rho GTPases. For background information on RHOBTBs, see RHOBTB1 (MIM 607351).

References

1. ^ GRCh38: Ensembl release 89: ENSG00000164292 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000021589 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Rivero F, Dislich H, Glöckner G, Noegel AA (Mar 2001). "The Dictyostelium discoideum family of Rho-related proteins". Nucleic Acids Research. 29 (5): 1068–79. doi:10.1093/nar/29.5.1068. PMC 29714. PMID 11222756.
6. Boureux A, Vignal E, Faure S, Fort P (Jan 2007). "Evolution of the Rho family of ras-like GTPases in eukaryotes". Molecular Biology and Evolution. 24 (1): 203–16. doi:10.1093/molbev/msl145. PMC 2665304. PMID 17035353.
7. ^ "Entrez Gene: RHOBTB3 Rho-related BTB domain containing 3".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
• Ramos S, Khademi F, Somesh BP, Rivero F (Oct 2002). "Genomic organization and expression profile of the small GTPases of the RhoBTB family in human and mouse". Gene. 298 (2): 147–57. doi:10.1016/S0378-1119(02)00980-0. PMID 12426103.
• Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW (Jun 2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature Biotechnology. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.

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