S26 may refer to:
Aviation
- Blériot-SPAD S.26, a French racing seaplane
- Philippine Air Lines Flight S26, which crashed in 1969
- Short S.26, a British flying boat transport
- Sikorsky S-26, a Russian biplane bomber
Rail and transit
- S26 (Berlin), a line of the Berlin S-Bahn
- Konbu Station, in Rankoshi, Isoya District, Hokkaido, Japan
- Rheineck–Walzenhausen mountain railway, a line of the St. Galen S-Bahn in Switzerland
- Tösstal railway line, a line of the Zürich S-Bahn in Switzerland
Roads
- Shanghai–Changzhou Expressway, China
- County Route S26 (California), United States
- U.S. Route 1 in New Jersey, partially numbered S26 until 1953
Submarines
- HMS Renown (S26), of the Royal Navy
- INS Vagsheer (S26), of the Indian Navy
- USS S-26 (SS-131), of the United States Navy
Other uses
- 40S ribosomal protein S26
- British NVC community S26, a swamps and tall-herb fens community in the British National Vegetation Classification system
- Djabwurrung language
- S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice, a safety phrase
- S26, a postcode district in Sheffield, England
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