Sammartino or Sanmartino is an Italian surname that may refer to:
- Bruno Sammartino (1935-2018), Italian-born American professional wrestler
- David Sammartino (born 1961), American professional wrestler, son of Bruno
- Fred Sammartino, American communication engineer and company executive
- Giuseppe Sanmartino (or Sammartino, 1720–1793), Italian sculptor
- Janis Lynn Sammartino (born 1950), American judge
- Marco Sammartino, late 17th-century Italian painter and etcher
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