Sinani is an Albanian surname. Notable people with the surname include:
- Danel Sinani (born 1997), Luxembourgish footballer
- Gazmend Sinani (1991–2018), Kosovo Albanian basketball player
- Ismet Sinani (born 1999), Kosovan footballer
- Sehid Sinani (born 1982), Swiss footballer
- Tahir Sinani (1964–2001), Albanian insurgent
- Vioresin Sinani (born 1977)
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