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TAPS (buffer)

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TAPS
Names
Preferred IUPAC name 3-{amino}propane-1-sulfonic acid
Other names N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.045.398 Edit this at Wikidata
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14)Key: YNLCVAQJIKOXER-UHFFFAOYSA-N
  • InChI=1/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14)Key: YNLCVAQJIKOXER-UHFFFAOYAP
SMILES
  • C(CNC(CO)(CO)CO)CS(=O)(=O)O
Properties
Chemical formula C7H17NO6S
Molar mass 243.27 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

TAPS (propanesulfonic acid) is a chemical compound commonly used to make buffer solutions.

It can bind divalent cations, including Co(II) and Ni(II).

TAPS is effective to make buffer solutions in the pH range 7.7–9.1, since it has a pKa value of 8.44 (ionic strength I = 0, 25 °C).

The pH (and pKa at I ≠ 0) of the buffer solution changes with concentration and temperature, and this effect may be predicted e.g. using online calculators.

References

  1. Machado, Carina M. M.; Gameiro, Paula; Soares, Helena M. V. M. (2008). "Complexation of M–(buffer)x–(OH)y systems involving divalent ions (cobalt or nickel) and zwitterionic biological buffers (AMPSO, DIPSO, TAPS and TAPSO) in aqueous solution". J. Solution Chem. 37 (5): 603–617. doi:10.1007/s10953-008-9265-3. S2CID 97906177.
  2. Goldberg, Robert N.; Kishore, Nand; Lennen, Rebecca M. (2002). "Thermodynamic quantities for the ionization reactions of buffers" (PDF). J. Phys. Chem. Ref. Data. 31 (2): 231–370. doi:10.1063/1.1416902.
  3. "Biological buffers". REACH Devices.
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