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Taleranol

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Chemical compound Pharmaceutical compound
Taleranol
Clinical data
Other namesP-1560; Teranol; β-Zearalanol
Identifiers
IUPAC name
  • (7S,11S)-7,15,17-Trihydroxy-11-methyl-12-oxabicyclooctadeca-1(14),15,17-trien-13-one
CAS Number
PubChem CID
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.164.729 Edit this at Wikidata
Chemical and physical data
FormulaC18H26O5
Molar mass322.401 g·mol
3D model (JSmol)
SMILES
  • C1CCC(O)CCCCCc2cc(O)cc(O)c2C(=O)O1
InChI
  • InChI=1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14-/m0/s1
  • Key:DWTTZBARDOXEAM-JSGCOSHPSA-N

Taleranol (INN, USAN) (developmental code name P-1560), or teranol, also known as β-zearalanol, is a synthetic, nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp which was never marketed. It is the β epimer of zeranol (α-zearalanol) and is a major metabolite of zeranol but with less biological activity.

See also

References

  1. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 350–. ISBN 978-1-4757-2085-3.
  2. ^ Yildiz F (16 December 2009). Advances in Food Biochemistry. CRC Press. pp. 233–. ISBN 978-1-4200-0769-5.
  3. Yu L, Wang S, Sun BG (28 October 2014). Food Safety Chemistry: Toxicant Occurrence, Analysis and Mitigation. CRC Press. pp. 240–. ISBN 978-1-4665-9795-2.


Xenoestrogens
Phytoestrogens
Flavanones
Flavones
Prenylflavonoids
Isoflavones
Isoflavanes
Dihydrochalcones
IsoflavenesGlabrene
Coumestans
Lignans
Flavonolignans
Flavonols
Others
Mycoestrogens
Derivatives
Synthetic
Metalloestrogens
  • Aluminium
  • Antimony
  • Arsenite
  • Barium
  • Cadmium
  • Chromium
  • Cobalt
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  • Lead
  • Mercury
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  • Selenite
  • Tin
  • Vanadate
Estrogen receptor modulators
ERTooltip Estrogen receptor
Agonists
Mixed
(SERMsTooltip Selective estrogen receptor modulators)
Antagonists
  • Coregulator-binding modulators: ERX-11
GPERTooltip G protein-coupled estrogen receptor
Agonists
Antagonists
Unknown
See also
Receptor/signaling modulators
Estrogens and antiestrogens
Androgen receptor modulators
Progesterone receptor modulators
List of estrogens


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