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Tetrahydromethanopterin S-methyltransferase

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tetrahydromethanopterin S-methyltransferase
Identifiers
EC no.2.1.1.86
CAS no.103406-60-6
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In enzymology, a tetrahydromethanopterin S-methyltransferase (EC 2.1.1.86) is an enzyme that catalyzes the chemical reaction

5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate {\displaystyle \rightleftharpoons } 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate

Thus, the two substrates of this enzyme are 5-methyl-5,6,7,8-tetrahydromethanopterin and 2-mercaptoethanesulfonate (coenzyme M), whereas its two products are 5,6,7,8-tetrahydromethanopterin and 2-(methylthio)ethanesulfonate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is 5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase. This enzyme is also called tetrahydromethanopterin methyltransferase. This enzyme participates in folate biosynthesis.

References

  • Sauer FD (April 1986). "Tetrahydromethanopterin methyltransferase, a component of the methane synthesizing complex of Methanobacterium thermoautotrophicum". Biochemical and Biophysical Research Communications. 136 (2): 542–7. doi:10.1016/0006-291X(86)90474-2. PMID 3085670.
Transferase: one carbon transferases (EC 2.1)
2.1.1: Methyl-
N-
O-
Homocysteine
Other
2.1.2: Hydroxymethyl-,
Formyl- and Related
Hydroxymethyltransferase
Formyltransferase
Other
2.1.3: Carboxy-
and Carbamoyl
Carboxy
Carbamoyl
2.1.4: Amidine
Enzymes
Activity
Regulation
Classification
Kinetics
Types
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