Tetrahydrosarcinapterin synthase

Tetrahydrosarcinapterin synthase (EC 6.3.2.33, H4MPT:alpha-L-glutamate ligase, MJ0620, MptN protein) is an enzyme with systematic name tetrahydromethanopterin:alpha-L-glutamate ligase (ADP-forming). This enzyme catalyses the following chemical reaction

ATP + tetrahydromethanopterin + L-glutamate

\rightleftharpoons

ADP + phosphate + 5,6,7,8-tetrahydrosarcinapterin

This enzyme catalyses the biosynthesis of 5,6,7,8-tetrahydrosarcinapterin.

References

Li H, Xu H, Graham DE, White RH (August 2003). "Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses". Proceedings of the National Academy of Sciences of the United States of America. 100 (17): 9785–90. Bibcode:2003PNAS..100.9785L. doi:10.1073/pnas.1733391100. PMC 187843. PMID 12909715.

External links

Tetrahydrosarcinapterin+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

v t e Enzymes: CO CS and CN ligases (EC 6.1-6.3)
6.1: Carbon-Oxygen	Aminoacyl tRNA synthetase Alanine Arginine Asparagine Aspartate Cysteine D-alanine—poly(phosphoribitol) ligase Glutamate Glutamine Glycine Histidine Isoleucine Leucine Lysine Methionine Phenylalanine Proline Serine Threonine Tryptophan Tyrosine Valine
6.2: Carbon-Sulfur	Succinyl coenzyme A synthetase Acetyl—CoA synthetase Long-chain-fatty-acid—CoA ligase
6.3: Carbon-Nitrogen	Glutamine synthetase Ubiquitin ligase Cullin Von Hippel–Lindau tumor suppressor UBE3A Mdm2 Anaphase-promoting complex UBR1 Glutathione synthetase CTP synthetase Adenylosuccinate synthase Argininosuccinate synthase Holocarboxylase synthetase GMP synthase Asparagine synthetase Carbamoyl phosphate synthetase I II Glutamate–cysteine ligase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Portal:

Biology

Category:

EC 6.3.2