Thermitase - Misplaced Pages

Thermitase (EC 3.4.21.66, thermophilic Streptomyces serine proteinase, Thermoactinomyces vulgaris serine proteinase) is an enzyme. This enzyme catalyses the following chemical reaction

Hydrolysis of proteins, including collagen

This peptidase is isolated from Thermoactinomyces vulgaris.

References

Mizusawa K, Yoshida F (November 1972). "Thermophilic Streptomyces alkaline proteinase. I. Isolation, crystallization, and physicochemical properties". The Journal of Biological Chemistry. 247 (21): 6978–84. PMID 5082135.
Borgia P, Campbell LL (December 1974). "Properties of two homologous alkaline proteases from Streptomyces rectus". Journal of Bacteriology. 120 (3): 1109–15. PMC 245889. PMID 4373436.
Kleine R (1982). "Properties of thermitase, a thermostable serine protease from Thermoactinomyces vulgaris". Acta Biologica et Medica Germanica. 41 (1): 89–102. PMID 7051706.
Meloun B, Baudyš M, Kostka V, Hausdorf G, Frömmel C, Höhne WE (1985). "Complete primary structure of thermitase from Thermoactinomyces vulgaris and its structural features related to the subtilisin-type proteinases". FEBS Lett. 183 (2): 195–200. doi:10.1016/0014-5793(85)80775-4.
Teplyakov AV, Kuranova IP, Harutyunyan EH, Vainshtein BK, Frömmel C, Höhne WE, Wilson KS (July 1990). "Crystal structure of thermitase at 1.4 A resolution". Journal of Molecular Biology. 214 (1): 261–79. doi:10.1016/0022-2836(90)90160-n. PMID 2196375.

External links

Thermitase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

v t e Endopeptidases: serine proteases/serine endopeptidases (EC 3.4.21)
Digestive enzymes	Enteropeptidase Trypsin Chymotrypsin Elastase Neutrophil Pancreatic
Coagulation	factors: Thrombin Factor VIIa Factor IXa Factor Xa Factor XIa Factor XIIa Kallikrein PSA KLK1 KLK2 KLK3 KLK4 KLK5 KLK6 KLK7 KLK8 KLK9 KLK10 KLK11 KLK12 KLK13 KLK14 KLK15 fibrinolysis: Plasmin Plasminogen activator Tissue plasminogen activator Urinary plasminogen activator
Complement system	Factor B Factor D Factor I MASP MASP1 MASP2 C3-convertase
Other immune system	Chymase Granzyme Tryptase Proteinase 3/Myeloblastin
Venombin	Ancrod Batroxobin
Other	Acrosin Prolyl endopeptidase Pronase Proprotein convertases 1 2 Prostasin Reelin Subtilisin/Furin/S1P4 Sedolisin/TPP1 Streptokinase Cathepsin A G

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Portal:

Biology

Category:

EC 3.4.21