Zanini is a surname. Notable people with the surname include:
- Marcel Zanini (1923–2023), French jazz clarinetist
- Mario Zanini (1907–1971), Brazilian painter and interior designer
- Nicola Zanini (born 1974), Italian footballer
- Stefano Zanini (born 1969), Italian cyclist
See also
- Zanin
- Carlos Zannini, Argentine politician
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