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::*To find secondary sources you can use pubmed and limit your search to review articles from the last 5 years. | ::*To find secondary sources you can use pubmed and limit your search to review articles from the last 5 years. | ||
:: Best ] (] · ] · ]) (if I write on your page reply on mine) 11:25, 21 July 2014 (UTC) | :: Best ] (] · ] · ]) (if I write on your page reply on mine) 11:25, 21 July 2014 (UTC) | ||
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Revision as of 11:51, 21 July 2014
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TwinkleI don't understand why my recent edit in cancer was reverted. Is it not relevant? Petergans (talk) 07:11, 10 July 2014 (UTC)
The Signpost: 09 July 2014
No Conflict with Secondary SourcesI will next put a review in, staying in line with medrs. I do not believe there is a secondary source for claims on Multiple Sclerosis or Autism. If you can find one, then please put it in. Since the effect on multiple sclerosis is so robust, I find your adherence to a guideline to be offensive in this case. 75.152.127.40 (talk) 12:10, 15 July 2014 (UTC)
2014 World Cancer ReportHi James. Could you possibly email me a copy of the above if you have it, please? --Anthonyhcole (talk · contribs · email) 02:15, 16 July 2014 (UTC)
CausesHi James. As the OP of the original thread, I just wanted to let you know (along with any interested talk-page stalkers) that I'm very interested to continue the discussion of the implications of that, but right now I'm pretty ko and it's not so easy for me to participate in the way I'd like. Hope to be back in a few days time. Fwiw, where I'm coming from is basically this: 1) yes, simple language is good; 2) but at the end of the day we need to make sure we (as Wikipedians) reflect rather than create; 3) maybe we need some tweaks to do this. Best, 109.157.86.177 (talk) 21:14, 16 July 2014 (UTC)
Medical Translation NewsletterWikiproject Medicine; Translation Taskforce Medical Translation Newsletter This is the first of a series of newsletters for Wikiproject Medicine's Translation Task Force. Our goal is to make all the medical knowledge on Misplaced Pages available to the world, in the language of your choice. note: you will not receive future editions of this newsletter unless you *sign up*; you received this version because you identify as a member of WikiProject MedicineSpotlight - Simplified article translation Wikiproject Medicine started translating simplified articles in February 2014. We now have 45 simplified articles ready for translation, of which the first on African trypanosomiasis or sleeping sickness has been translated into 46 out of ~100 languages. This list does not include the 33 additional articles that are available in both full and simple versions. Our goal is to eventually translate 1,000 simplified articles. This includes:
We are looking for subject area leads to both create articles and recruit further editors. We need people with basic medical knowledge who are willing to help out. This includes to write, translate and especially integrate medical articles. What's happening?
I've (CFCF) taken on the role of community organizer for this project, and will be working with this until December. The goals and timeline can be found here, and are focused on getting the project on a firm footing and to enable me to work near full-time over the summer, and part-time during the rest of the year. This means I will be available for questions and ideas, and you can best reach me by mail or on my talk page.
For those going to London in a month's time (or those already nearby) there will be at least one event for all medical editors, on Thursday August 7th. See the event page, which also summarizes medicine-related presentations in the main conference. Please pass the word on to your local medical editors.
There has previously been some resistance against translation into certain languages with strong Misplaced Pages presence, such as Dutch, Polish, and Swedish.
Integration is the next step after any translation. Despite this it is by no means trivial, and it comes with its own hardships and challenges. Previously each new integrator has needed to dive into the fray with little help from previous integrations. Therefore we are creating guides for specific Wikis that make integration simple and straightforward, with guides for specific languages, and for integrating on small Wikis. Instructions on how to integrate an article may be found here News in short
ResearchHey Doc James, I wanted to get your opinion on something re: endometrial cancer. I really appreciate your help over there, by the way! :) I've been relying pretty heavily throughout on Comprehensive Gyn, which has some discussion of current research into immunotherapy for endometrial cancer. Since the textbook obviously meets MEDRS, is it okay to include a section on some research (using tamoxifen for Her2/neu positive cancers and instigating a tumor-specific response in papillary serous carcinoma, among others)? I can send you the chapter if you don't have it and want to see what I'm working with. Thanks! Keilana| 00:06, 17 July 2014 (UTC)
Cannabis (drug)#HistoryYou reverted an edit citing WP:MEDMOS but it's unclear to me what part of MEDMOS you believe indicates that a history section cannot be moved up closer to the top of the article. Can you explain, please? Perhaps there's something in there I missed. Msnicki (talk) 18:15, 17 July 2014 (UTC)
GastroenterologyWhy did you do this revert? It seems like a reasonable addition to the article.--Srleffler (talk) 23:33, 17 July 2014 (UTC)
July 2014You currently appear to be engaged in an edit war according to the reverts you have made on Cannabis (drug). Users are expected to collaborate with others, to avoid editing disruptively, and to try to reach a consensus rather than repeatedly undoing other users' edits once it is known that there is a disagreement.Please be particularly aware, Misplaced Pages's policy on edit warring states:
If you find yourself in an editing dispute, use the article's talk page to discuss controversial changes; work towards a version that represents consensus among editors. You can post a request for help at an appropriate noticeboard or seek dispute resolution. In some cases it may be appropriate to request temporary page protection. If you engage in an edit war, you may be blocked from editing. Msnicki (talk) 00:50, 18 July 2014 (UTC)
Surrogate outcomeI wish to complain about the flags made by Formerly 98 in the article "surrogate outcome". Formerly 98 finds the article is unbalanced and against the pharmaceutical industry. He found the part benefits of surrogate outcomes was too "small". He finds there are not enough secondary source references in the part examples of surrogate outcomes, despite the multitude of references and cross references. Please compare to the article "clinical outcomes" which has only 4 low quality references. He finds I never answer tho his complaints and 1 week later he refuses to answer to my responses. See at the talk page. I responded point by point. To make the article more balanced he added a table with fourteen FDA approved drugs in 2008-2009 on surrogate outcomes and he looked for their meaningful outcomes. Only two drugs possibly added value: the arthemeter combination and an antiviral for HIV. So this makes the text no more balanced. I added content to the section benefits to expand it from 26 lines to 50. For me the value of surrogate outcomes in rct's is obvious, you can find them everywhere in the litterature. But for him this is not enough. Formerly 98 also finds surrogate outcomes have nothing to do with adverse events of treatments. For this reason he deleted many of the examples. He added content to the parts of hepatitis C and B which makes them unreadable. He added meta analyses which combined (few) rcts, prospective studies and cc studies as proof of efficacy. But in his user page he says he hates meta analyses... But in fact he doesn't know the difference between a cochrane systematic review and a meta analysis. I cite formerly 98: "The statement "Systematic reviews should not present surrogate outcome data as their primary analysis" is clearly not mainstream as 90% of published meta analyses do exactly that. The article should be mostly representative of mainstream opinion." Formerly 98 doesn't understand what a surrogate is. In the figure added by him he confounds a treatment (cardiovascular revascularisation) with a surrogate (coronarography). I asked him to correct it. He didn't answer. As an expert on antibiotics (ciprofloxacin) he says: " Antibiotic trials are performed on the basis of the well established surrogate endpoints of physical signs and symptoms of infection. If we required a mortality endpoint in every clinical trial, the shortage of new antibiotics would become more acute, as the cost of developing drugs for infections that have mortality <10% with the current standard of care would rise into the billions of dollars." Again he confounds the surrogate MIC, culture antibiogram with the meaningfull clinical outcome which is resolving of the symptoms, (morbidity) and mortality. He thinks only mortality is a clinical meaningfull outcome. I asked also to revise the importance of the item surrogate outcome. I wanted also to make a new article "meaningful (real) clinical outcome". Is this possible? The article "clinical outcome" should be completely revised. Formerly 98 found "The problems throughout are WP:OR, WP:OS and WP:COAT." My answer was:
So i ask you to discuss al those things with other editors, and to give me advise how to proceed further, because formerly 98 doesn't want to discuss with me anymore, and he certainly will not remove flags. Formerly 98 last lines were: "You've written 165 KB of rambling, opinionated editorial that no one is going to read anyway, and its not really worth my while to spend any more time trying to introduce some balance. I'll focus my efforts on articles that are likely to be read." Recently i got two stroop wafles from JPW and someone else for the high value of my content. I added content to more than 40 articles. Sincerely yours --Truebreath (talk) 14:48, 18 July 2014 (UTC)
The Signpost: 16 July 2014
Robyn Roche-Paull, BS, IBCLC, La Leche League Leader, USNHer IBCLC means that she studied tertiary sources. Her page cites primary sources. She verified the primary sources with original research. Her claim follows from earlier claims in the article that nursing on demand increases supply. Where do you get off making claims against her reliability? 108.181.136.221 (talk) 02:00, 19 July 2014 (UTC)
KetamineHi, I'd like to thank you for taking a legitimate interest in accurate knowledge about Ketamine. Sounds like we may be sharing some of the same interests. I would make you aware of the following situation - the use of ketamine to treat physical and emotional pain is exploding in the US. Where there were a couple of clinics 18 months ago, there are now dozens of commercial clinics and probably hundreds of physicians in private practice trying ketamine. To get an idea, we run one of the first clinics and have as PATIENTS three physicians, two psychologists and two psychiatric nurses. There are literally over a thousand patients who have been treated successfully for depression on a clinical basis in the US. We have several patients from Canada that come to our Scottsdale, AZ clinic. Unfortunately, most clinics are not oriented to keeping good enough outcome measures to support publishable results. On the research level, most of the money and time in pharma in now spent on neurogenesis and how to duplicate that portion of the functionality of ketamine. Very, very little of that research is published and available for citing as it is proprietary and used in drug development. Wiki is seriously out of touch with the reality on the ground. My concerns are: 1. Many prospective providers will look at a couple of published single dose studies and wiki and then hang out their shingle. That is not going to end up well as it stands.
2. Many prospective patients are going to go to wiki first. The reality is that 95% of people think ketamine was developed and primarily used as a horse tranquilizer, that it has few legitimate uses for people, that it invariably causes hallucinations. The list goes on. People are going to stay sick and other people are going to die because the wiki definition does not put those preconceptions to rest. The opposite risk must also be managed, the unattainable attempt by people to self-medicate with a medication that requires careful monitoring to be safe and effective.
These are a few examples of the problematic areas:
Thanks again for your time and interest in the subject. Ger Gaines Geraldwgaines (talk) 19:52, 19 July 2014 (UTC)
Off label usesDo you agree we put all off label uses in Europe AND US, for which there is no definitive proof in the section society and culture? Look at gabapentin were a myriad of uses were cited. For the reader this must be problematic. If some indication becomes a true benefit we can change it to uses. For instance gabapentin and hot flashes: is one good trial sufficient to put it in the uses section? Gabapentin has been used a lot for migrain profylaxis, but there is no evidence for it. Should it be in uses???? I don't think so. --Truebreath (talk) 09:30, 20 July 2014 (UTC)
do you mean not to put off label uses in Europe and US in the section society and culture? do you mean to put profylaxis of migraine in uses, if it is proven that it doesn't help?? could we make a section evidence based uses?and other uses if the evidence is lacking... So is one narrative review in an obscure journal sufficient to put an indication in uses??? and should the title of the uses of gabapentin be "pain" if we have only proof for neuropathic pain ? I think this is an important discussion. sincerely yours --Truebreath (talk) 12:16, 20 July 2014 (UTC)
I looked for gabapentin at the dutch version https://nl.wikipedia.org/Gabapentine Indicaties Het wordt voorgeschreven: voor de behandeling van epilepsie wordt gabapentine meestal slechts gebruikt als andere eerste-keusmiddelen onvoldoende werken of te veel bijwerkingen geven; tegen zenuwpijnen (neuropathische pijn en neurogene pijn), postherpetische neuralgie (pijn na gordelroos) en fantoompijn. Gabapentine blijkt ook te werken tegen postoperatieve pijn en in hoge dosis is het ook geschikt voor de behandeling van essentiële tremor. at the Deutsh version https://de.wikipedia.org/Gabapentin Anwendungsgebiete Gabapentin ist zur Monotherapie von einfachen und komplexen partiellen Anfällen mit und ohne sekundäre Generalisierung und zur Zusatztherapie von partiellen Anfällen mit und ohne sekundäre Generalisierung zugelassen. Eine weitere Indikation ist die Behandlung neuropathischer Schmerzen. Neuropathische Schmerzen entstehen z. B. bei einem Teil der Patienten mit einer Gürtelrose nach Abklingen der Hautveränderungen, der Post-Zoster-Neuralgie. Ein anderes häufiges Anwendungsgebiet ist die diabetische Polyneuropathie sowie die Behandlung von Phantomschmerzen. Auch postoperative Schmerzen können durch Gabapentin gemildert werden. Die Substanz kann auch bei refraktärem Husten wirken, wenn die Ursache keine anderen Maßnahmen erfordert. Im Rahmen von "off-label use" (also außerhalb des in der Zulassung genehmigten Gebrauchs) kann es auch bei Spastik bei Multipler Sklerose eingesetzt werden, wenn mit den dafür zugelassenen Substanzen bei angemessener Dosierung und Anwendungsdauer keine ausreichende Linderung erzielt werden konnte oder Unverträglichkeit vorliegt. Ein Beschluss des Gemeinsamen Bundesausschuss (G-BA) zur Verordnungsfähigkeit in nicht zugelassenem Anwendungsgebiet ist im März 2014 in Kraft getreten. at the French version https://fr.wikipedia.org/Gabapentine antiépileptique ; dans le traitement des douleurs neuropathiques telles la neuropathie diabétique et la neuropathie post-herpétique comme co-analgésique à des dérivés morphiniques dans le cadre de douleurs cancéreuses neuropathiques3 ; soulagement de la douleur neurotrope associée à la maladie de Lyme (des douleurs chroniques dites neuropathiques surviennent chez 10–15% of patients victimes d'une neuroborreliose due à Borrelia burgdorferi All those versions speak about neuropathic or neurogenic (polyneuropathy) pain. Not pain in general. I think we should not put uses from reviews from obscure journals, with low grade peer review, in general and certainly not for these drugs, because there is risk of abuse and intoxication. "there is increasing published evidence of concern about the abuse of pregabalin and gabapentin, and these drugs are now commonly being detected in toxicology in autopsies after drug overdoses. So what is the motivation to misuse these drugs? Users describe the effects as the “ideal psychotropic drug,” “great euphoria,” “disassociation,” and “opiate buzz,” and are achieving these effects by taking large quantities as a single dose.10 Accordingly there is a growing black market, and these drugs are being bought through online pharmacies. The US recognises the problems associated with pregabalin, which has now become a scheduled drug under the Controlled Substance Act" Sincerely yours --Truebreath (talk) 21:08, 20 July 2014 (UTC)
This edition of baby colicSince somebody has flagged you for edit warring, I think you should stay out of twinkle for a while, because the edition I am talking about defends a lie with twinkle, since fast and thoughtful are an unusual combination. I found it hard to be civil after the edition in my subject, because the inclusion exaggerates one line in an abstract by clarifying it and amplifying it. That iz not a paraphrasal: That iz a distorted quotation. It is consistent with your bias against extending the list of disease protections that breast milk offers. I could add that consuming human milk reduces a baby's risk for dying of diarrhea by somewhere between fourteen (exclusively formula-fed) and four (supplemented) to one (exclusively breast-fed. In my arrogant opinion if baby colic and diarrhea occur together, then changing the diet of a baby younger than six months, procuring donor milk, iz mandatory. 172.219.255.66 (talk) 22:28, 20 July 2014 (UTC)
Baby colic is not usually associated with diarrhea. If there is severe diarrhea it is likely not colic. Diarrhea is also not a complication of colic. Doc James (talk · contribs · email) (if I write on your page reply on mine) 03:36, 21 July 2014 (UTC)
Notice of Neutral point of view noticeboard discussionHello, Jmh649. This message is being sent to inform you that there currently is a discussion at Misplaced Pages:Neutral point of view/Noticeboard regarding an issue with which you may have been involved. Thank you.
July 2014 2Your recent editing history at Myofascial meridians shows that you are currently engaged in an edit war. Being involved in an edit war can result in your being blocked from editing—especially if you violate the three-revert rule, which states that an editor must not perform more than three reverts on a single page within a 24-hour period. Undoing another editor's work—whether in whole or in part, whether involving the same or different material each time—counts as a revert. Also keep in mind that while violating the three-revert rule often leads to a block, you can still be blocked for edit warring—even if you don't violate the three-revert rule—should your behavior indicate that you intend to continue reverting repeatedly.To avoid being blocked, instead of reverting please consider using the article's talk page to work toward making a version that represents consensus among editors. See BRD for how this is done. If discussions reach an impasse, you can then post a request for help at a relevant noticeboard or seek dispute resolution. In some cases, you may wish to request temporary page protection.
Copy and pastingYou added the text "The American Medical Association takes no position specifically on acupuncture" in this edit which is exactly the same as the source . If this occurs again you will lose your ability to edit. You must paraphrase. Doc James (talk · contribs · email) (if I write on your page reply on mine) 02:47, 21 July 2014 (UTC)
Reply to your commentHi Doc James, my name is Daniela, and I saw that you left me a message on July 7th referring to my post on Selective Serotonin Reuptake Inhibitors, in the "Reverse effects" section, in "Cardiovascular" subsection. You said: Please use high quality references per WP:MEDRS such as review articles or major textbooks. Note that review articles are NOT the same as peer reviewed articles. A good place to find medical sources is TRIP database Thanks. I saw that my post is not there anymore. I suppose is because, as you said in your comment, I used peer-review articles, which I did not know it was not allowed. Can you tell me where can I find this restriction and if it was because of this that my post was delated? Thanks for your attention and help. Sincerely, DanielaDanimora22 (talk) 11:20, 21 July 2014 (UTC) ==Notice of Edit warring noticeboard discussion== Hello. This message is being sent to inform you that there is currently a discussion involving you at Misplaced Pages:Administrators' noticeboard/Edit warring regarding a possible violation of Misplaced Pages's policy on edit warring. Thank you. |