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{{short description|Italian biologist}} |
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{{short description|Italian biologist}} |
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{{Multiple issues| |
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'''Paola Leone''', ], is a leading researcher of ], a ]. |
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{{Update|reason= Leone stopped working with the organization even before it shut down in 2014.|date=May 2024}} |
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{{Notability|1=Academics|date=November 2022}} |
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{{Third-party|date=November 2022}} |
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'''Paola Leone''' is an Italian researcher of ], a ]. |
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Leone was born and raised in ], ]. She received her undergraduate and graduate training in Italy, followed by post-doctoral studies in ] and ] in ]. She holds a doctorate degree in Neuroscience from the ].<ref>University of Medicine and Dentistry of New Jersey - </ref> Her work on Canavan disease started at Yale, where she collaborated with other early pioneers in ]. She left Yale in 1998 to join the (now defunct) Cell & Gene Therapy Center at ] in ] She now directs The Cell & Gene Therapy Center at the ].<ref>University of Medicine and Dentistry of New Jersey - {{webarchive|url=https://archive.today/20090325090141/http://som.umdnj.edu/cgtweb/faculty/ |date=2009-03-25 }}.</ref><ref>{{Cite web|title=On the cusp of a cure for deadly childhood disease|url=https://today.rowan.edu/news/2020/11/on-the-cusp-of-a-cure-for-deadly-childhood-disease.html|access-date=2020-12-28|website=today.rowan.edu|language=en}}</ref><ref>{{Cite web|last=Ph.D|first=Miryam Z. Wahrman|title=Looking for cures|url=https://jewishstandard.timesofisrael.com/looking-for-cures/|access-date=2020-12-28|website=jewishstandard.timesofisrael.com|language=en-US}}</ref> |
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Leone was born and raised in ], ]. She received her undergraduate and graduate training in Italy, followed by post-doctoral studies in ] and ] in ]. She holds a doctorate degree in Neuroscience from the ].<ref>University of Medicine and Dentistry of New Jersey - </ref> Her work on Canavan disease started at Yale, where she collaborated with other early pioneers in ]. She left Yale in 1998 to join the (now defunct) Cell & Gene Therapy Center at ] in ]. She directs The Cell & Gene Therapy Center at the ].<ref>University of Medicine and Dentistry of New Jersey - {{webarchive|url=https://archive.today/20090325090141/http://som.umdnj.edu/cgtweb/faculty/ |date=2009-03-25 }}.</ref><ref>{{Cite web|title=On the cusp of a cure for deadly childhood disease|url=https://today.rowan.edu/news/2020/11/on-the-cusp-of-a-cure-for-deadly-childhood-disease.html|access-date=2020-12-28|website=today.rowan.edu|language=en}}</ref><ref>{{Cite web|last=Ph.D|first=Miryam Z. Wahrman|title=Looking for cures|url=https://jewishstandard.timesofisrael.com/looking-for-cures/|access-date=2020-12-28|website=jewishstandard.timesofisrael.com|language=en-US}}</ref> |
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Recently, she has been funded by ]-] and Jacob's Cure to study the potential of subpopulations of stem cells to promote remyelination and phenotypic rescue in animal models of white matter disease, including the Canavan mouse model. She is currently generating pre-clinical data using human Embryonic-Derived-Oligodendrocyte Stem Cells provided by ] (CA). These studies will provide a foundation for a targeted and comprehensive analysis of the potential of a cell-based therapy for ].<ref></ref> |
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Recently,{{when?|date=November 2022}} she has been funded by ]-] and Jacob's Cure to study the potential of subpopulations of stem cells to promote remyelination and phenotypic rescue in animal models of white matter disease, including the Canavan mouse model. She is generating pre-clinical data using human Embryonic-Derived-Oligodendrocyte Stem Cells provided by ] (CA). These studies will provide a foundation for a targeted and comprehensive analysis of the potential of a cell-based therapy for ].<ref></ref> |
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==References== |
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==References== |
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