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{{Short description|Abnormal connection between two epithelialized surfaces, often organs}}
{{Infobox_Disease |
{{About|the anatomical term|the former legume subgenus|Cassia (genus)|the metal straw used in Catholic liturgy|Fistula (liturgical object)}}
Name = {{PAGENAME}} |
{{Distinguish|Vistula}}
DiseasesDB = |
{{use dmy dates|date=May 2023}}
ICD10 = |
{{Infobox medical condition
ICD9 = |
ICDO = | | name = Fistula
OMIM = | | image = Colocutaneous Fistula.PNG
| caption = Abdominal ] with right colocutaneous fistula and associated subcutaneous ]
MedlinePlus = |
| field = ]
eMedicineSubj = |
| pronounce = {{IPAc-en|ˈ|f|ɪ|s|tj|ʊ|l|ə}}<ref name=OED> {{Webarchive|url=https://web.archive.org/web/20211208152021/https://www.oed.com/public/online/about-oed- |date=2021-12-08 }}. '']'' 2nd edition, 1989. {{subscription required}}</ref><ref name=Webster>{{cite web |title=Definition of Fistula |url=https://www.merriam-webster.com/dictionary/fistula |website=www.merriam-webster.com |access-date=28 December 2020 |language=en |archive-date=24 April 2009 |archive-url=https://web.archive.org/web/20090424032545/https://www.merriam-webster.com/dictionary/fistula |url-status=live }}</ref>
eMedicineTopic = |
MeshID = D005402 | | symptoms =
| complications =
| onset =
| duration =
| types =
| causes =
| risks =
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| differential =
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In medicine, a '''fistula''' (pl. fistulas or fistulae) is an abnormal connection or passageway between two epithelium-lined organs or vessels that normally do not connect.


<!-- Definition -->
==Location of fistulas==
In ], a '''fistula''' ({{plural form}}: '''fistulas''' or '''fistulae''' {{IPAc-en|-|l|i|,_|-|l|ai}}; from ] ''fistula'', "tube, pipe") is an abnormal ] (i.e. tube) joining two hollow spaces (technically, two ] surfaces), such as ]s, ]s, or other hollow ] to each other, often resulting in an abnormal flow of fluid from one space to the other.<ref name=Webster/><ref name="NAFC">{{cite web |title=What Is A Fistula? Types, causes and treatments explained. |url=https://www.nafc.org/fistula |website=Urinary incontinence education; National Association for Continence |access-date=28 December 2020 |archive-date=29 November 2014 |archive-url=https://web.archive.org/web/20141129170541/https://www.nafc.org/fistula |url-status=live }}</ref><ref name="Garefalakis Hickey Johnson 2017 pp. 342–353">{{cite book | last1=Garefalakis | first1=Maria | last2=Hickey | first2=Martha | last3=Johnson | first3=Neil | title=International Encyclopedia of Public Health | chapter=Gynecological Morbidity | url=https://books.google.com/books?id=WAnpCgAAQBAJ|publisher=Elsevier | year=2016 | isbn=978-0-12-803678-5|editor-last=Quah|editor-first=Stella R.| doi=10.1016/b978-0-12-803678-5.00178-8 | edition=Second|pages=342–353 |editor-last2=Cockerham|editor-first2=William C.| quote=A fistula is an abnormal connection or passageway between organs or vessels that are not normally connected.}}</ref> <!-- Classification --> An ] connects the ] to the ] skin. An anovaginal or ] is a hole joining the anus or ] to the ]. A colovaginal fistula joins the space in the colon to that in the vagina. A urinary tract fistula is an abnormal opening in the ] or an abnormal connection between the urinary tract and another organ. An abnormal communication (i.e. hole or tube) between the ] and the ] is called a ], while if it is between the bladder and the vagina it is known as a ], and if between the ] and the vagina: a urethrovaginal fistula. When occurring between two parts of the intestine, it is known as an enteroenteral fistula, between the ] and the skin it is known as an enterocutaneous fistula, and between the colon and the skin as a colocutaneous fistula.<ref name="NAFC" />
Fistulas can develop in various parts of the body. The following list is sorted by the ].


<!-- Causes -->
===H: Diseases of the eye, adnexa, ear, and mastoid process===
A fistula can result from an infection, inflammation, injury or surgery.<ref name=Rao/> Many result from complications during childbirth. Sometimes a fistula is deliberately surgically created as part of a treatment, for example in the case of an ] for ].<ref name=Mayo>{{Cite web|url=https://www.mayoclinic.org/diseases-conditions/arteriovenous-fistula/symptoms-causes/syc-20369567|title=Arteriovenous fistula - Symptoms and causes|website=Mayo Clinic|language=en|access-date=2019-12-05|archive-date=2020-11-26|archive-url=https://web.archive.org/web/20201126041434/https://www.mayoclinic.org/diseases-conditions/arteriovenous-fistula/symptoms-causes/syc-20369567|url-status=live}}</ref>
*(H04.6) ]
*(H70.1) ]
**]: between the ] and a ]
*(H83.1) ]
**]: tear between the membranes between the middle and inner ]


<!-- Treatment -->
===I: Diseases of the circulatory system===
The treatment for a fistula varies depending on the type, cause, and severity of the fistula, but often involves surgical intervention combined with ] therapy. In some cases the fistula is temporarily covered using a fibrin glue or plug. A catheter may be required to drain a fistula.<ref name="NAFC" />
*(I25.4) ], acquired
*(I28.0) ] of ]
**]: between an artery and vein of the ], resulting in ] of ]. This results in improperly oxygenated blood.
*(I67.1) Cerebral ], acquired
*(I77.0) ], acquired
*(I77.2) Fistula of ]


<!-- Epidemiology -->
===J: Diseases of the respiratory system===
Globally, every year between 50,000 and 100,000 women are affected by one or more fistulas relating to childbirth.<ref name="WHO2018" /> Typically they are vaginal fistulas, between either the bowel or bladder and the vaginal canal, but uterine and bowel fistulas also occur.
*(J86.0) ] with fistula
*(J95.0) ] following ]: between the breathing and the feeding tubes


<!-- Botany -->In ], the term is most common in its adjectival forms, where it is used in ] to refer to a species that is distinguished by one or more hollow or tubular structures. '']'', for example, has tubular flowers.<ref name="Lamiaceae"> {{Webarchive|url=https://web.archive.org/web/20160304192225/http://pick4.pick.uga.edu/nh/tx/Plantae/Dicotyledoneae/Lamiaceae/Monarda/fistulosa/Identification.html |date=2016-03-04 }} subpage of {{Webarchive|url=https://web.archive.org/web/20160304192225/http://pick4.pick.uga.edu/nh/tx/Plantae/Dicotyledoneae/Lamiaceae/Monarda/fistulosa/Identification.html |date=2016-03-04 }} , 2014.</ref>
===K: Diseases of the digestive system===
]
*(K11.4) Fistula of ]
*(K31.6) Fistula of ] and ]
*(K31.6) ]
*(K31.6) ]
**]: between the intestine and the skin surface, namely from the ] or the ] or the ]. This definition excludes the fistulas arising from the ] or the ].
**]: from the ] to the skin surface
*(K38.3) ]
*({{ICD10|K|60|3|k|55}}) ]
**({{ICD10|K|60|3|k|55}}) ]: connecting the ] or other ] area to the ] surface. This results in abnormal discharge of ] through an opening other than the ]. Also called '''fistula-in-ano'''.
***'''Fecal fistula''': see Anorectal
***'''Fistula-in-ano''': see Anorectal
*({{ICD10|K|60|4|k|55}}) ]
*({{ICD10|K|60|5|k|55}}) ]
*(K63.2) Fistula of ]
**]: between two parts of the ]
*(K82.3) Fistula of ]
*(K83.3) Fistula of ]
**]: connecting the ] ducts to the skin surface, often caused by ] surgery
**]: between the ] and the exterior via the ]


<!-- Society and culture -->The term was first used in the 14th century.<ref name="Webster" />
===M: Diseases of the musculoskeletal system and connective tissue===
*(M25.1) Fistula of ]


==Definition==
===N: Diseases of the genitourinary system===
A fistula is an abnormal ] between ] or ] that do not usually connect. It can be due to a disease or trauma, or purposely surgically created.<ref name="NAFC"/><ref name=Rao>{{Cite book|last=Rao|first=Jyotsna|chapter-url=https://books.google.com/books?id=yn17DwAAQBAJ&pg=PA256|title=Qrs for Bds III Year-E Book|date=2019|publisher=Elsevier Health Sciences|isbn=978-81-312-5535-3|edition=Third|pages=256|language=en|chapter=Section II. General Surgery: Wounds, Sinuses, Fistulae}}</ref>
*(N32.1) ]
*(N36.0) ]
**]:between the ] and the outside of the body
*(N64.0) ]
*(N82) ] / ]
**(N82.0) ]: between the ] and the ]
**(N82.1) Other ]
***''']: abnormal opening in the ]
**(N82.2) ]
***]: between the ] and the ]
**(N82.3) ]
***]: between the ] and the ]
**(N82.4) Other ]
**(N82.5) ]
**(N82.8) Other ]
**(N82.9) ], unspecified


==Classification==
===Q: Congenital malformations, deformations and chromosomal abnormalities===
Various types of fistulas include:
*(Q18.0) ], fistula and ] of ]
* {{Anchor|Blind fistula}}'''Blind:''' Only one open end; may also be called sinus tracts.<ref name=Rao/>
**] Preauricular fistula: A small pit in front of the ]. Also called Fistula Auris Congenita or ].
* {{Anchor|Complete fistula}}'''Complete:''' Both internal and external openings.<ref name=Rao/>
*(Q26.6) ]-] fistula
* {{Anchor|Incomplete fistula}}'''Incomplete:''' An external skin opening that does not connect to any internal organ.<ref name=Rao/>
*(Q38.0) ] fistula of ]
*(Q38.4) ] fistula of ]
*(Q42.0) ] ], ] and ] of ] with fistula
*(Q42.2) ] ], ] and ] of ] with fistula
*(Q43.6) ] fistula of ] and ]
*(Q51.7) ] fistulae between ] and ] and ]
*(Q52.2) ] ]


Although most fistulas are in forms of a tube, some can also have multiple branches.<ref>{{Cite journal |last=Abou-Zeid |first=Ahmed A. |date=2011-07-28 |title=Anal fistula: Intraoperative difficulties and unexpected findings |journal=World Journal of Gastroenterology |language=en |volume=17 |issue=28 |pages=3272–3276 |doi=10.3748/wjg.v17.i28.3272 |doi-access=free |pmc=3160529 |pmid=21876613}}</ref>
===T: External causes===
*(T14.5) ]
*(T81.8) ]


===Location===
==Types of fistulas==
Types of fistula can be described by their location. Anal fistulas connect between the epithelialized surface of the anal canal and the perianal skin. Anovaginal or rectovaginal fistulas occur when a hole develops between the anus or rectum and the vagina. Colovaginal fistulas occur between the colon and the vagina. Urinary tract fistulas are abnormal openings within the urinary tract or an abnormal connection between the urinary tract and another organ such as between the bladder and the uterus in a vesicouterine fistula, between the bladder and the vagina in a vesicovaginal fistula, and between the urethra and the vagina in urethrovaginal fistula. When occurring between two parts of the intestine, it is known as an enteroenteral fistula, between the small intestine and the skin as an enterocutaneous fistula, and between the small intestine and the colon as a colocutaneous fistula.<ref name="NAFC"/>


The following list is sorted by the ].
Various types of fistulas include:


===H: Diseases of the eye, adnexa, ear, and mastoid process===
*'''Blind''': with only one open end
* (H04.6) ]
*'''Complete''': with both external and internal openings
* (H05.81) ]
*'''Incomplete''': a fistula with an external skin opening, which does not connect to any internal organ
* (H70.1) ]
** ]: between the ] and a ]
* (H83.1) ]
** ]: tear between the membranes between the middle and inner ears
* ]
** ]: usually on the top of the ] of the ears


===I: Diseases of the circulatory system===
Although most fistulas are in forms of a tube, some can also have multiple branches.
* (I25.4) ], acquired
* (I28.0) ] of ]
** ]: between an artery and vein of the ], resulting in ] of blood. This results in improperly oxygenated blood.
* (I67.1) Cerebral ], acquired
* (I77.0) ], acquired
* (I77.2) Fistula of ]


===J: Diseases of the respiratory system===
==Causes==
* (J86.0) ] with fistula
* (J95.0) ], between the ] and the ]. This may be ] or acquired, for example as a complication of a ].


===K: Diseases of the digestive system===
Various causes of fistula are:
]
* (K11.4) ]
* (K31.6) Fistula of stomach and duodenum
* (K31.6) ]
* (K31.6) ] – after a ] a fistula forms between the transverse colon and the upper jejunum (which, post Billroth II, is attached to the remainder of the stomach). Fecal matter passes improperly from the colon to the stomach and causes ].
** ]: between the intestine and the skin surface, namely from the ] or the ] or the ]. This definition excludes the fistulas arising from the ] or the ].
** ]: from the stomach to the skin surface
* (K38.3) ]
* ({{ICD10|K|60}}) Anal and rectal fissures and fistulas
** ({{ICD10|K|60|3}}) ]
** ({{ICD10|K|60|5}}) ] (fecal fistula, fistula-in-ano): connecting the ] or other ] area to the ] surface. This results in abnormal discharge of ] through an opening other than the ].
* (K63.2) Fistula of intestine
** ]: between two parts of the intestine
* (K82.3) Fistula of ]
* (K83.3) Fistula of ]
** ]: connecting the bile ducts to the skin surface, often caused by gallbladder surgery
** ]: between the ] and the exterior via the ]


===M: Diseases of the musculoskeletal system and connective tissue===
*'''Diseases''': Inflammatory bowel diseases, such as ] and ], are the leading causes of anorectal, enteroenteral, and enterocutaneous fistulas. A person with severe stage-3 ] will also develop fistulas.
* (M25.1) Fistula of ]


===N: Diseases of the urogenital system===
*'''Medical treatment''': Complications from gallbladder surgery can lead to biliary fistula. Radiation therapy can lead to vesicovaginal fistula. An arteriovenous fistula can be deliberately created, as described below in ''therapeutic use''.
* (N32.1) ]
* (N36.0) ]
** ]:between the ] and the outside of the body
* (N64.0) ]
* (N82) ] / ]
** (N82.0) ]: between the ] and the ]
** (N82.1) Other ]
*** ]: abnormal opening in the ]
** (N82.2) ]
*** ]: between the ] and the vagina
** (N82.3) ]
*** ]: between the ] and the vagina
** (N82.4) Other ]
** (N82.5) ]
** (N82.8) Other ]
** (N82.9) ], unspecified


===Q: Congenital malformations, deformations and chromosomal abnormalities===
*'''Trauma''': Head trauma can lead to ]s, whereas trauma to other parts of the body can cause arteriovenous fistulas. Obstructed labor can lead to vesicovaginal and rectovaginal fistulas. An ] develops when blood supply to the tissues of the vagina and the bladder (and/or rectum) is cut off during prolonged obstructed labor. The tissues die and a hole forms through which urine and/or feces pass uncontrollably. Vesicovaginal and rectovaginal fistulas cay also be caused by rape, in particular gang rape, and rape with foreign objects, as evidenced by the abnormally high number of women in conflict areas who have suffered fistulae.<ref></ref><ref></ref>
* (Q18.0) ], fistula and cyst of ]
** ] preauricular fistula: A small pit in front of the ]. Also known as an ear pit or ].
* (Q26.6) ]-] fistula
* (Q38.0) Congenital fistula of lip
* (Q38.4) Congenital fistula of ]
* (Q42.0) Congenital absence, ] and ] of ] with fistula
* (Q42.2) Congenital absence, ] and ] of ] with fistula
* (Q43.6) Congenital fistula of ] and ]
* (Q51.7) Congenital fistulae between ] and ] and ]s
* (Q52.2) Congenital ]


===T: External causes===
* In 2003, thousands of women in eastern Congo presented themselves for treatment of traumatic fistula caused by systematic, violent gang rape that occurred during the country's five years of war. So many cases have been reported that the destruction of the vagina is considered a war injury and recorded by doctors as a crime of combat.<ref></ref>
* (T14.5) ]
* (T81.8) ]


== Treatment == ==Causes==
* '''Disease:''' Infections including an ] and inflammatory diseases including ] and ] can result in fistulas.<ref name="UCLA">{{cite web |title=Fistulas: What are Fistulas? Fistulas Symptoms, Treatment, Diagnosis - UCLA |url=https://www.uclahealth.org/womens-pelvic-health/fistulas |website=www.uclahealth.org |access-date=29 December 2020 |archive-date=10 April 2020 |archive-url=https://web.archive.org/web/20200410134356/https://www.uclahealth.org/womens-pelvic-health/fistulas |url-status=live }}</ref><ref name="Carr2020">{{cite journal |last1=Carr |first1=S |last2=Velasco |first2=AL |title=Fistula In Ano |date=January 2020 |pmid=32491449 |url=https://pubmed.ncbi.nlm.nih.gov/32491449/ |publisher=StatPearls Publishing |access-date=2020-12-29 |archive-date=2023-01-12 |archive-url=https://web.archive.org/web/20230112091716/https://pubmed.ncbi.nlm.nih.gov/32491449/ |url-status=live }}</ref> Fistulas to the anus may occur in ].<ref name="JemecRevuz2006">{{cite book|last1=Seksik|first1=Philippe|chapter-url=https://books.google.com/books?id=hpKFsXwcKlgC&pg=PA53|title=Hidradenitis Suppurativa|last2=Contou|first2=Jean-Francois|last3=Cosnes|first3=Anne|last4=Cosnes|first4=Jacques|publisher=Springer|year=2006|isbn=978-3-540-33100-1|editor-last=Jemec|editor-first=Gregor B. E.|page=53|chapter=7. Hidradenitis Suppurativa and Crohn's Disease|editor-last2=Revuz|editor-first2=Jean|editor-last3=Leyden|editor-first3=James J.}}</ref> In women, fistulas can also occur following pelvic infection and inflammation.<ref name="UCLA"/>
]
* '''Surgical and medical treatment:''' Complications from ] surgery can lead to biliary fistulas.<ref name="Crespi Montecamozzo Foschi 2021 p. ">{{cite journal | last1=Crespi | first1=M. | last2=Montecamozzo | first2=G. | last3=Foschi | first3=D. | title=Diagnosis and Treatment of Biliary Fistulas in the Laparoscopic Era | journal=Gastroenterology Research and Practice | volume=2016 | date=2021-06-02 | pages=1–6 | pmid=26819608 | doi=10.1155/2016/6293538 | pmc=4706943 | doi-access=free }}</ref> As well as being congenital or resulting from trauma, ]s are created purposefully for ].<ref name=Mayo/> Radiation therapy to the pelvis can lead to vesicovaginal fistulas.<ref name="UCLA"/> Persistent gastrocutaneous fistulas can develop after ].<ref>Singhal, Shashideep MD2; Malieckal, Anju MD2; Culliford, Andrea MD1 Over the Scope Clip (OTSC) Closure of Persistently Leaking Gastrocutaneous Fistula after Failed Conventional Endoscopic Clipping Presidential Poster, American Journal of Gastroenterology: October 2012 - Volume 107 - Issue - p S532-S533</ref>
* '''Trauma:''' Prolonged childbirth can lead to fistulas in women, in whom abnormal connections may occur between the bladder and vagina, or the rectum and vagina.<ref name="UCLA"/> An ] develops when blood supply to the tissues of the vagina and the bladder (and/or rectum) is cut off during prolonged obstructed labor. The tissues die and a hole forms through which urine and/or feces pass uncontrollably. ] and ]s may also be caused by rape, in particular gang rape, and rape with foreign objects, as evidenced by the abnormally high number of women in conflict areas who have developed fistulae.<ref>{{Cite web |url=http://www.msmagazine.com/spring2005/congo.asp |title=Stephanie Nolen, "Not Women Anymore…" Ms. Magazine, Spring 2005 |access-date=2007-12-11 |archive-url=https://web.archive.org/web/20170120063703/http://www.msmagazine.com/spring2005/congo.asp |archive-date=2017-01-20 |url-status=dead }}</ref><ref>{{Cite web |url=http://www.unfpa.org/news/news.cfm?ID=816 |title=UNFPA: United Nations Population Fund. Press Release, 22 June 2006. "More Funding Needed to Help Victims of Sexual Violence" |access-date=11 December 2007 |archive-date=4 October 2012 |archive-url=https://web.archive.org/web/20121004160531/http://www.unfpa.org/news/news.cfm?ID=816 |url-status=live }}</ref> In 2003, thousands of women in eastern ] presented themselves for treatment of traumatic fistulas caused by systematic, violent gang rape, often also with sharp objects that occurred during the country's five years of war. So many cases have been reported that the destruction of the vagina is considered a war injury and recorded by doctors as a crime of combat.<ref></ref> Head trauma can lead to ]s, whereas trauma to other parts of the body can cause arteriovenous fistulas.<ref name="Nagpal Ahmed Cuschieri 2021 p. ">{{cite journal | last1=Nagpal | first1=Kamal | last2=Ahmed | first2=Kamran | last3=Cuschieri | first3=RJ | title=Diagnosis and management of acute traumatic arteriovenous fistula | journal=The International Journal of Angiology | volume=17 | issue=4 | date=2021-06-02 | pages=214–216 | pmid=22477453 | doi=10.1055/s-0031-1278313 | pmc=2728918 }}</ref>


== Treatment ==
Treatment for fistulae varies depending on the cause and extent of the fistula, but often involves surgical intervention combined with ] therapy.


Treatment for fistula varies depending on the cause and extent of the fistula, but often involves surgical intervention combined with ] therapy. In some cases the fistula is temporarily covered, using a fibrin glue or plug. Catheters may be required to drain a fistula.<ref name="NAFC"/>
Typically the first step in treating a fistula is an examination by a doctor to determine the extent and "path" that the fistula takes through the tissue.


Surgery is often required to assure adequate drainage of the fistula (so that ] may escape without forming an ]). Various surgical procedures are used, most commonly ], placement of a ] (a cord that is passed through the path of the fistula to keep it open for draining), or an endorectal flap procedure (where healthy tissue is pulled over the internal side of the fistula to keep feces or other material from reinfecting the channel).<ref name="Golub 1997 pp. 487–491">{{cite journal | last=Golub | first=R | title=Endorectal mucosal advancement flap: the preferred method for complex cryptoglandular fistula-in-ano | journal=Journal of Gastrointestinal Surgery | publisher=Elsevier BV | volume=1 | issue=5 | year=1997 | issn=1091-255X | doi=10.1016/s1091-255x(97)80138-2 | pages=487–491| pmid=17061335 | s2cid=19188977 }}</ref>
In some cases the fistula is temporarily covered, for example a fistula caused by ] is often treated with a ] to delay the need for surgery to a more appropriate age.


Management involves treating any underlying causative condition. For example, surgical treatment of fistulae in ] can be effective, but if the Crohn's disease itself is not treated, the rate of recurrence of the fistula is very high (well above 50%).
Surgery is often required to assure adequate drainage of the fistula (so that ] may escape without forming an ]). Various surgical procedures are commonly used, most commonly ], placement of a ] (a cord that is passed through the path of the fistula to keep it open for draining), or an endorectal flap procedure (where healthy tissue is pulled over the internal side of the fistula to keep feces or other material from reinfecting the channel). Treatments involving filling the fistula with fibrin glue or plugging it with plugs made of porcine small intestine submucosa have also been explored in recent years, with variable success. Surgery for anorectal fistulae is not without side effects, including recurrence, reinfection, and incontinence.


== Therapeutic use ==
It is important to note that surgical treatment of a fistula without diagnosis or management of the underlying condition, if any, is not recommended. For example, surgical treatment of fistulae in ] can be effective, but if the Crohn's disease itself is not treated, the rate of recurrence of fistula is very high (well above 50%).
In people with ], requiring dialysis, a ] is often deliberately created in the arm by means of a short day surgery in order to permit easier withdrawal of blood for ].{{citation needed|date=December 2021}}


As a radical treatment for ], surgical creation of a portacaval fistula produces an anastomosis between the ] and the ] across the omental foramen (of Winslow). This spares the portal venous system from high pressure which can cause esophageal varices, ]e, and hemorrhoids.{{citation needed|date=December 2021}}
== Therapeutic use ==


==Epidemiology==
In ] patients, a ] is often deliberately created in the arm by means of a short day surgery in order to permit easier withdrawal of blood for ].
Globally, every year between 50,000 and 100,000 women are affected by fistula relating to childbirth.<ref name="WHO2018">{{cite web |title=Obstetric fistula |url=https://www.who.int/news-room/facts-in-pictures/detail/10-facts-on-obstetric-fistula |website=www.who.int |language=en |access-date=2020-12-28 |archive-date=2019-08-25 |archive-url=https://web.archive.org/web/20190825012718/https://www.who.int/features/factfiles/obstetric_fistula/en/ |url-status=live }}</ref>


==Botany==
As a radical treatment for ], surgical creation of a portacaval fistula produces an anastomosis between the ] and the ] across the omental foramen (of Winslow). This spares the portal venous system from high pressure which can cause esophageal varices, caput madusae, and hemorrhoids.
In ], the term is most common in its adjectival forms, where it is used in ] to refer to species that are distinguished by hollow or tubular structures. '']'', for example, has tubular flowers;<ref name=Lamiaceae/> '']'' has a tubular stem; '']'' has hollow or tubular leaves, and '']'' subsp. ''fistula'' is the subspecies with hollow spines.{{citation needed|date=December 2020}}


== See also == == Society and culture ==
The term was first used in the 14th century.<ref name=Webster/>


A fistula plays a central role in ]s play ]
* ]

==See also==
* {{annotated link|Alexis St. Martin}}
* ]
* {{annotated link|M. Ijaiya's technique}}
* ]
* ]


== References == == References ==
{{Reflist}}


{{Reflist|30em}}
== External links ==

*
==External links==
*
*{{commonscatinline}}
*
{{Medical resources
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| DiseasesDB =
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*
| ICD9 =
*
| ICDO =
*
| OMIM =
| MedlinePlus = 002365
| eMedicineSubj =
| eMedicineTopic =
| MeshID = D005402
}}


{{Authority control}}
*
*
* on fistulae in conflict areas in the Democratic Republic of the Congo
* , a Newsweek article on fistulae in conflict areas in the Democratic Republic of the Congo
*
*
* , IRIN, 16 November, 2005
]


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Latest revision as of 14:29, 30 December 2024

Abnormal connection between two epithelialized surfaces, often organs This article is about the anatomical term. For the former legume subgenus, see Cassia (genus). For the metal straw used in Catholic liturgy, see Fistula (liturgical object). Not to be confused with Vistula.

Medical condition
Fistula
Abdominal CT scan with right colocutaneous fistula and associated subcutaneous pneumatosis
Pronunciation
SpecialtyGeneral surgery

In anatomy, a fistula (pl.: fistulas or fistulae /-li, -laɪ/; from Latin fistula, "tube, pipe") is an abnormal connection (i.e. tube) joining two hollow spaces (technically, two epithelialized surfaces), such as blood vessels, intestines, or other hollow organs to each other, often resulting in an abnormal flow of fluid from one space to the other. An anal fistula connects the anal canal to the perianal skin. An anovaginal or rectovaginal fistula is a hole joining the anus or rectum to the vagina. A colovaginal fistula joins the space in the colon to that in the vagina. A urinary tract fistula is an abnormal opening in the urinary tract or an abnormal connection between the urinary tract and another organ. An abnormal communication (i.e. hole or tube) between the bladder and the uterus is called a vesicouterine fistula, while if it is between the bladder and the vagina it is known as a vesicovaginal fistula, and if between the urethra and the vagina: a urethrovaginal fistula. When occurring between two parts of the intestine, it is known as an enteroenteral fistula, between the small intestine and the skin it is known as an enterocutaneous fistula, and between the colon and the skin as a colocutaneous fistula.

A fistula can result from an infection, inflammation, injury or surgery. Many result from complications during childbirth. Sometimes a fistula is deliberately surgically created as part of a treatment, for example in the case of an arteriovenous fistula for hemodialysis.

The treatment for a fistula varies depending on the type, cause, and severity of the fistula, but often involves surgical intervention combined with antibiotic therapy. In some cases the fistula is temporarily covered using a fibrin glue or plug. A catheter may be required to drain a fistula.

Globally, every year between 50,000 and 100,000 women are affected by one or more fistulas relating to childbirth. Typically they are vaginal fistulas, between either the bowel or bladder and the vaginal canal, but uterine and bowel fistulas also occur.

In botany, the term is most common in its adjectival forms, where it is used in binomial names to refer to a species that is distinguished by one or more hollow or tubular structures. Monarda fistulosa, for example, has tubular flowers.

The term was first used in the 14th century.

Definition

A fistula is an abnormal connection between vessels or organs that do not usually connect. It can be due to a disease or trauma, or purposely surgically created.

Classification

Various types of fistulas include:

  • Blind: Only one open end; may also be called sinus tracts.
  • Complete: Both internal and external openings.
  • Incomplete: An external skin opening that does not connect to any internal organ.

Although most fistulas are in forms of a tube, some can also have multiple branches.

Location

Types of fistula can be described by their location. Anal fistulas connect between the epithelialized surface of the anal canal and the perianal skin. Anovaginal or rectovaginal fistulas occur when a hole develops between the anus or rectum and the vagina. Colovaginal fistulas occur between the colon and the vagina. Urinary tract fistulas are abnormal openings within the urinary tract or an abnormal connection between the urinary tract and another organ such as between the bladder and the uterus in a vesicouterine fistula, between the bladder and the vagina in a vesicovaginal fistula, and between the urethra and the vagina in urethrovaginal fistula. When occurring between two parts of the intestine, it is known as an enteroenteral fistula, between the small intestine and the skin as an enterocutaneous fistula, and between the small intestine and the colon as a colocutaneous fistula.

The following list is sorted by the International Statistical Classification of Diseases and Related Health Problems.

H: Diseases of the eye, adnexa, ear, and mastoid process

I: Diseases of the circulatory system

J: Diseases of the respiratory system

K: Diseases of the digestive system

Duodeno Biliary Fistula

M: Diseases of the musculoskeletal system and connective tissue

N: Diseases of the urogenital system

Q: Congenital malformations, deformations and chromosomal abnormalities

T: External causes

Causes

Probed surgically excised gastrocutaneous fistula tract, that resulted from a previous gastrostomy tube.
  • Surgical and medical treatment: Complications from gallbladder surgery can lead to biliary fistulas. As well as being congenital or resulting from trauma, arteriovenous fistulas are created purposefully for hemodialysis. Radiation therapy to the pelvis can lead to vesicovaginal fistulas. Persistent gastrocutaneous fistulas can develop after gastrostomy.
  • Trauma: Prolonged childbirth can lead to fistulas in women, in whom abnormal connections may occur between the bladder and vagina, or the rectum and vagina. An obstetric fistula develops when blood supply to the tissues of the vagina and the bladder (and/or rectum) is cut off during prolonged obstructed labor. The tissues die and a hole forms through which urine and/or feces pass uncontrollably. Vesicovaginal and rectovaginal fistulas may also be caused by rape, in particular gang rape, and rape with foreign objects, as evidenced by the abnormally high number of women in conflict areas who have developed fistulae. In 2003, thousands of women in eastern Congo presented themselves for treatment of traumatic fistulas caused by systematic, violent gang rape, often also with sharp objects that occurred during the country's five years of war. So many cases have been reported that the destruction of the vagina is considered a war injury and recorded by doctors as a crime of combat. Head trauma can lead to perilymph fistulas, whereas trauma to other parts of the body can cause arteriovenous fistulas.

Treatment

Treatment for fistula varies depending on the cause and extent of the fistula, but often involves surgical intervention combined with antibiotic therapy. In some cases the fistula is temporarily covered, using a fibrin glue or plug. Catheters may be required to drain a fistula.

Surgery is often required to assure adequate drainage of the fistula (so that pus may escape without forming an abscess). Various surgical procedures are used, most commonly fistulotomy, placement of a seton (a cord that is passed through the path of the fistula to keep it open for draining), or an endorectal flap procedure (where healthy tissue is pulled over the internal side of the fistula to keep feces or other material from reinfecting the channel).

Management involves treating any underlying causative condition. For example, surgical treatment of fistulae in Crohn's disease can be effective, but if the Crohn's disease itself is not treated, the rate of recurrence of the fistula is very high (well above 50%).

Therapeutic use

In people with kidney failure, requiring dialysis, a cimino fistula is often deliberately created in the arm by means of a short day surgery in order to permit easier withdrawal of blood for hemodialysis.

As a radical treatment for portal hypertension, surgical creation of a portacaval fistula produces an anastomosis between the hepatic portal vein and the inferior vena cava across the omental foramen (of Winslow). This spares the portal venous system from high pressure which can cause esophageal varices, caput medusae, and hemorrhoids.

Epidemiology

Globally, every year between 50,000 and 100,000 women are affected by fistula relating to childbirth.

Botany

In botany, the term is most common in its adjectival forms, where it is used in binomial names to refer to species that are distinguished by hollow or tubular structures. Monarda fistulosa, for example, has tubular flowers; Eutrochium fistulosum has a tubular stem; Allium fistulosum has hollow or tubular leaves, and Acacia seyal subsp. fistula is the subspecies with hollow spines.

Society and culture

The term was first used in the 14th century.

A fistula plays a central role in William Shakespeares play All's Well That Ends Well

See also

References

  1. Oxford English Dictionary Archived 2021-12-08 at the Wayback Machine. OED 2nd edition, 1989. (subscription required)
  2. ^ "Definition of Fistula". www.merriam-webster.com. Archived from the original on 24 April 2009. Retrieved 28 December 2020.
  3. ^ "What Is A Fistula? Types, causes and treatments explained". Urinary incontinence education; National Association for Continence. Archived from the original on 29 November 2014. Retrieved 28 December 2020.
  4. Garefalakis, Maria; Hickey, Martha; Johnson, Neil (2016). "Gynecological Morbidity". In Quah, Stella R.; Cockerham, William C. (eds.). International Encyclopedia of Public Health (Second ed.). Elsevier. pp. 342–353. doi:10.1016/b978-0-12-803678-5.00178-8. ISBN 978-0-12-803678-5. A fistula is an abnormal connection or passageway between organs or vessels that are not normally connected.
  5. ^ Rao, Jyotsna (2019). "Section II. General Surgery: Wounds, Sinuses, Fistulae". Qrs for Bds III Year-E Book (Third ed.). Elsevier Health Sciences. p. 256. ISBN 978-81-312-5535-3.
  6. ^ "Arteriovenous fistula - Symptoms and causes". Mayo Clinic. Archived from the original on 26 November 2020. Retrieved 5 December 2019.
  7. ^ "Obstetric fistula". www.who.int. Archived from the original on 25 August 2019. Retrieved 28 December 2020.
  8. ^ Identification of Monarda fistulosa Archived 2016-03-04 at the Wayback Machine subpage of Discover Life Archived 2016-03-04 at the Wayback Machine , 2014.
  9. Abou-Zeid, Ahmed A. (28 July 2011). "Anal fistula: Intraoperative difficulties and unexpected findings". World Journal of Gastroenterology. 17 (28): 3272–3276. doi:10.3748/wjg.v17.i28.3272. PMC 3160529. PMID 21876613.
  10. ^ "Fistulas: What are Fistulas? Fistulas Symptoms, Treatment, Diagnosis - UCLA". www.uclahealth.org. Archived from the original on 10 April 2020. Retrieved 29 December 2020.
  11. Carr, S; Velasco, AL (January 2020). "Fistula In Ano". StatPearls Publishing. PMID 32491449. Archived from the original on 12 January 2023. Retrieved 29 December 2020. {{cite journal}}: Cite journal requires |journal= (help)
  12. Seksik, Philippe; Contou, Jean-Francois; Cosnes, Anne; Cosnes, Jacques (2006). "7. Hidradenitis Suppurativa and Crohn's Disease". In Jemec, Gregor B. E.; Revuz, Jean; Leyden, James J. (eds.). Hidradenitis Suppurativa. Springer. p. 53. ISBN 978-3-540-33100-1.
  13. Crespi, M.; Montecamozzo, G.; Foschi, D. (2 June 2021). "Diagnosis and Treatment of Biliary Fistulas in the Laparoscopic Era". Gastroenterology Research and Practice. 2016: 1–6. doi:10.1155/2016/6293538. PMC 4706943. PMID 26819608.
  14. Singhal, Shashideep MD2; Malieckal, Anju MD2; Culliford, Andrea MD1 Over the Scope Clip (OTSC) Closure of Persistently Leaking Gastrocutaneous Fistula after Failed Conventional Endoscopic Clipping Presidential Poster, American Journal of Gastroenterology: October 2012 - Volume 107 - Issue - p S532-S533
  15. "Stephanie Nolen, "Not Women Anymore…" Ms. Magazine, Spring 2005". Archived from the original on 20 January 2017. Retrieved 11 December 2007.
  16. "UNFPA: United Nations Population Fund. Press Release, 22 June 2006. "More Funding Needed to Help Victims of Sexual Violence"". Archived from the original on 4 October 2012. Retrieved 11 December 2007.
  17. Emily Wax, Washington Post Foreign Service. Saturday, October 25, 2003; Page A01 "A Brutal Legacy of Congo War"
  18. Nagpal, Kamal; Ahmed, Kamran; Cuschieri, RJ (2 June 2021). "Diagnosis and management of acute traumatic arteriovenous fistula". The International Journal of Angiology. 17 (4): 214–216. doi:10.1055/s-0031-1278313. PMC 2728918. PMID 22477453.
  19. Golub, R (1997). "Endorectal mucosal advancement flap: the preferred method for complex cryptoglandular fistula-in-ano". Journal of Gastrointestinal Surgery. 1 (5). Elsevier BV: 487–491. doi:10.1016/s1091-255x(97)80138-2. ISSN 1091-255X. PMID 17061335. S2CID 19188977.

External links

  • Media related to Fistulae at Wikimedia Commons
ClassificationD
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